Work Placement I
First co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.
Work Placement II
Second co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.
Work Placement III
Third co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.
Work Placement IV
Optional Co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.
Work Placement V
Optional Co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.
Chemical Principles and Properties
A chemical approach to describing the natural world. Molecular structure, shapes, and behaviour of molecules emphasizing organic compounds. Bonding and intermolecular interactions; the states of matter; solutions and their properties. Thermochemistry, entropy, free energy, chemical equilibrium, and reaction rates. Labs emphasize chemical syntheses, stoichiometry, and modern analytical techniques.
Lectures, 3 hours per week; plus a minimum of six 3-hour labs per term.
Prerequisite: a minimum 70 percent grade in Grade 12U chemistry (or equivalent course), CHEM 1P00, or permission of the Department.
Introductory Chemistry
Fundamental principles of chemistry. Topics include atomic structure and the periodic table, names and formulas of chemical compounds, principles of chemical bonding, types of chemical reactions, and basic chemical calculations. Tutorials emphasize the development and practice of problem solving skills.
Lectures, 3 hours per week; lab, tutorial and problems solving session, 3 hours per week.
Note: not open to students with 70 percent or greater in Grade 12U chemistry (or equivalent course). CHEM 1P00 is designed to assist those with insufficient background in chemistry to succeed in CHEM 1F92. Students with less than 70 percent in Grade 12U chemistry, or who have not taken an advanced high school chemistry course are allowed take CHEM 1F92 instead of CHEM 1P00 by permission of the Department if they pass a written test of basic chemistry knowledge, to be administered before classes begin.
Chemical Principles and Properties
General chemistry, stoichiometry, inorganic and organic structures and reactions. Laboratory work includes chemical purification and analysis.
Lectures, 3 hours per week; plus a minimum of six 3-hour labs.
Restriction: open to CAST majors.
Introduction to Modern Physical Chemistry
Phase equilibrium; gas phase kinetics; electronic structure of atoms and molecules; interaction of light with matter.
Lectures, 3 hours per week; tutorial, 1 hour per week; plus a minimum of six 3-hour labs.
Prerequisites: CHEM 1F92; MATH 1P01 and 1P02 (preferred), or MATH 1P97.
Principles of Organic Chemistry I
An introduction to the principles and techniques of organic chemistry; correlation of reactions and physical properties of organic compounds with structure and energetic concepts. Introduction to applications of spectroscopy in organic chemistry and biochemistry. Selected experiments in organic preparations and techniques.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 1F92.
Principles of Organic Chemistry II
Introduction to aromatic molecules and electrophilic aromatic substitution reactions. Chemistry of natural products, their origin and biological significance. Topics include concepts of carbonyl and carbohydrate chemistry, DNA and an introduction to amino acids and proteins. Selected experiments in organic synthesis, and characterization and analysis.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 2P20.
Principles of Inorganic Chemistry
A survey of the periodic table stressing periodicity of chemical behaviour. Chemistry and reactions in aqueous solutions; structure and bonding in simple compounds; applications to biological and environmental processes.
Lectures, 3 hours per week; plus a minimum of six 3-hour labs.
Prerequisite: CHEM 1F92.
Introduction to Analytical Chemistry
Introduction to separation methods such as chromatography, solvent extraction and precipitation; use of buffers for pH-control; statistical treatment of analytical data including normal distributions, significance testing and linear regression.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 1F92.
Introduction to Biophysical Chemistry
(also offered as BTEC 2P63)
Physical chemistry as applied to biological sciences. Introductory thermodynamics, kinetics, equilibria, and transport phenomena as applied to proteins, biological membranes and other biological systems. Laboratory work includes kinetic measurements, equilibrium constant measurements and protein purification and characterization.
Lectures, lab, 6 hours per week.
Prerequisites: CHEM 1F92; MATH 1P01 and 1P02 (preferred), or MATH 1P97.
Undergraduate Research
Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory.
Restriction: open to CHEM (single or combined) majors and permission of the Department.
Note: if both CHEM 2P98 and CHEM 3P98 are taken, only one of these may be based on work done in the department.
Structure and Reactivity of Organic Molecules
Methods for functional group manipulation including oxidation, reduction and the use of protecting groups in organic chemistry. General methods for carbon-carbon bond formation emphasizing three dimensional structure and mechanism. Modern methods of asymmetric synthesis. Selected experiments in synthetic organic chemistry and the handling of air and water sensitive reagents.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 2P21 or permission of the Department.
Note: CHEM 3P40 recommended. May be taken concurrently.
Organic Reactions
The chemistry of amines, heterocyclic and heteroaromatic compounds. Pericyclic reactions and reactive intermediates. Molecular rearrangements, peptide synthesis and protecting groups, design of organic synthesis. Introduction to organic photochemistry and the chemistry of carbenes.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 3P20.
Main Group Inorganic Chemistry
Systematic inorganic and organometallic chemistry of the transition elements, emphasizing structure, bonding and reactivity in inorganic and organometallic compounds. Selected experiments in inorganic and organometallic synthesis; use of modern structural methods for determination of composition, structure and bonding.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 2P32.
Note: CHEM 3P40 recommended. May be taken concurrently.
Completion of this course will replace previous assigned grade and credit obtained in CHEM 3P32.
Transition Metal Chemistry
Continuation of CHEM 3P30, emphasizing the main group elements.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 3P30 (3P32).
Note: CHEM 3P40 recommended. May be taken concurrently.
Spectroscopic Techniques for Structure Elucidation
Use of instrumental methods for the determination of structures of molecules. Techniques will include mass spectrometry, nuclear magnetic resonance spectroscopy, covered Fourier transform infrared spectroscopy, visible and UV spectroscopy, computerized data manipulation. Molecular modelling software may be included for three-dimensional visualization of complex molecules.
Lectures, tutorial, 6 hours per week.
Restriction: students must have a minimum of 9.0 overall credits.
Prerequisite: CHEM 2P20.
Instrumental Methods for Quantitative Analysis
Use of instrumental methods for quantitative determination of elements and molecular species. Techniques include chromatography, atomic spectrometry, X-ray fluorescence spec-trometry, nuclear emission and neutron-activation analysis, introduction to electroanalytical techniques. Emphasis on sample preparation and cleanup and aspects of quality assurance/quality control.
Lectures, lab, 6 hours per week.
Restriction: students must have a minimum of 9.0 overall credits.
Prerequisite: CHEM 2P42.
Quantum Chemistry
Schrodinger equation, solution of the harmonic oscillator problem, hydrogen atom, angular momentum theory, variational method with applications to atomic and molecular systems, molecular orbital theory and simple group theory. Introduction to FORTRAN 77.
Lectures, 3 hours per week; lab, 2 hours per week; tutorial, 1 hour per week.
Atomic and Molecular Structure and Spectroscopy
Group theory and theory of electro-magnetic radiation and spectroscopic transitions. Rotational and vibrational spectroscopy (Microwave, IR, Raman); atomic and molecular electronic spectroscopy (UV/Visible); magnetic resonance (NMR, EPR); X-ray crystallography.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 3P51.
Industrial Chemistry
Principles and practice of industrial chemistry. A survey of the chemical industry, pollution control, plant design, corrosion and similar topics. Selected industrial processes will be discussed in detail. Tours of chemical plants and industrial laboratories.
Lectures, 3 hours per week; seminars and plant tours, 3 hours per week.
Prerequisite: one credit from CHEM 2P12, 2P20, 2P32, 2P42, 2P63.
Bio-organic Chemistry
(also offered as BTEC 3P62)
Mechanistic description of the biosynthesis and metabolism of natural products including alkaloids, terpenes and acetate-derived compounds. Selected examples of biologically/medicinally active classes of natural products along with their physiological modes of activity.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 2P21.
Protein and Nucleic Acid Chemistry
(also offered as BTEC 3P63)
Structure and chemistry of proteins and nucleic acids. Selected aspects of transcription, translation, protein folding, post-translational modification, targeting, synthesis and sequencing, and detection techniques.
Lectures, lab, 6 hours per week.
Prerequisite: CHEM 2P21.
Undergraduate Research
Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory.
Restriction: open to CHEM (single or combined) majors with 9.0 overall credits and permission of the Department.
Note: if both CHEM 2P98 and CHEM 3P98 are taken, only one of these may be based on work done in the department.
Research Project
Experimental or theoretical research to be carried out under faculty supervision.
Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair.
Prerequisite: CHEM 3P40 or 3P41.
Co-requisite: CHEM 4F91.
Thesis
The thesis incorporates the results of the research in CHEM 4F90 and forms the basis for a seminar to be presented by the student.
Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair.
Prerequisite: CHEM 3P40 or 3P41.
Co-requisite: CHEM 4F90.
Special Topics
Tutorials, seminars, special projects or directed readings in an area of chemistry.
Lectures/seminar/ tutorial, 3 hours per week.
Restriction: open to CHEM (single or combined) majors with a minimum of 14.0 overall credits and permission of the Chair.
Statistical Thermodynamic in Chemistry and Biology
Ensembles, entropy, free energy, statistical mechanics of simple gases and solids, heat capacity, chemical equilibrium, substrate binding, water as a solvent, and polymers and biopolymers.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P51.
Co-requisite: CHEM 3P53.
Biophysical Photochemistry
Principles of light induced processes such as electron, energy and signal transfer and their role in biological systems. Marcus theory, Dexter and Foerster mechanisms of energy transfer. The optical and magnetic resonance spectroscopy of excited states.
Lectures, 3 hours per week.
Prerequisite: CHEM 3P40, 3P53 or permission of the instructor.
Computational Chemistry: Applications in Biotechnology
(also offered as BTEC 4P18)
Structure-based drug design, molecular modelling, conformational search techniques, secondary and tertiary protein structure prediction, quantitative structure activity relationships and bioinformatics.
Lectures, 3 hours per week.
Restriction: students must have a minimum of 13.5 overall credits.
Prerequisite: CHEM 2P12 or 2P63.
Organic Reactions and Synthesis
The disconnection approach to organic synthesis. Problems of chemo-, regio- and stereo-selectivity. Appreciation of elaborate syntheses. Synthetic organic chemistry topics from the recent literature.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P21.
Organic Reactions and Mechanisms
Topics include conformational analysis, introduction to transition state theory and the description of stereo and electronic control in organic reactions. Pertinent applications will be taken from the recent literature.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P21.
Organometallics in Organic Synthesis
Use of organometallic reagents for organic transformations. Metalation and trans-metalation using organolithium, magnesium, cerium and zinc reagents; stable precursors and reactive intermediates in transition metal catalyzed organic reactions employing palladium, nickel, ruthenium, and other metals. Topics from recent literature involving applications to organic synthesis, emphasizing stereoselectivity.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P21.
Enzyme and Co-enzyme Mechanisms
(also offered as BTEC 4P27)
Hydrolytic and other processes catalyzed by enzymes lacking non-protein prosthetic groups; transferase reactions involving biotin, pyridoxal phosphate, thiamine pyrophosphate, folic acid and cobalamin; oxidation mechanisms involving pyridine nucleotides, flavoenzymes, hydroperoxidases and oxgenases.
Lectures, seminar, 3 hours per week.
Prerequisites: CHEM 2P21, BCHM 3P01and 3P02.
Advanced Inorganic and Organometallic Chemistry
Continuation of CHEM 3P30 and 3P31 focussing on advanced topics of inorganic and organometallic chemistry of main group and transition metal elements, emphasizing the use of modern physical methods for determination of composition, structure and bonding of inorganic and organometallic compounds.
Lectures, 3 hours per week.
Prerequisite: CHEM 3P31 and CHEM 3P53.
Note: CHEM 3P53 may be taken concurrently with permission of the instructor.
Bio-inorganic Chemistry
Principles governing selection, uptake, storage, transport, and role of metal ions in biological processes. Topics include electron-transfer systems, substrate binding and activation by nonredox enzymes, metal-containing drugs, and biomineralization.
Lectures, seminar, 3 hours per week.
Restriction: students must have a minimum of 12.0 overall credits.
Prerequisites: CHEM 2P21 and 2P32.
Enviro-Analytical Chemistry
Chemical speciation studied by a variety of modern analytical techniques. Transport and fate of various compounds and elements in the environment.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P41.
Biophysical Techniques
(also offered as BCHM 4P67 and BTEC 4P67)
Modern instrumental methods of biotechnology emphasizing understanding theory. Development of newer technologies which utilize biological components. Topics include optical, X-ray and NMR techniques, separation techniques, hybridization assays, immunoassays, biosensors and mass spectral techniques; membrane chemistry.
Lectures, seminar, 3 hours per week.
Prerequisites: CHEM 2P21 and 2P63 or permission of the instructor.
Biotransformations
(also offered as BTEC 4P68)
The organic reactions carried out by isolated enzymes, fungal cultures and bacteria. The production of pharmaceutical, agricultural and industrial chemicals by biological processes.
Lectures, 3 hours per week.
Prerequisite: one of CHEM 3P20, 3P62, 3P63 or permission of the instructor.
Library Research and Seminar
Detailed study of the scientific literature under faculty supervision.
Restriction: open to students in the BSc with a Major in Chemistry program with a minimum of 15.0 overall credits or permission of the Department.
Note: the results of the study will be written up in a major essay and presented as a formal seminar.