Publications

Department of Chemistry




Publications

  1. “Theory-guided design of Brønsted acid-assisted phosphine catalysis: synthesis of dihydropyrones from aldehydes and allenoates” Creech,G.S.,  Zhu, X. Fonovic, B.,  Dudding, T, Kwon, O. Tetrahedron 2008, 64 (29), 6935-6942.
  2. “Origin of Enantioselection in Hetero-Diels−Alder Reactions Catalyzed by Naphthyl-TADDOL” Anderson, C. D.; Dudding, T.; Gordillo, R.; Houk, K. N. Org. Lett. 2008, 10 (13), 2749-2752.
  3. “An Experimental and Theoretical Study of the Asymmetric Lithiation of 1,2,3,5,6,7-Hexahydro-3a,4a-diazacyclopenta[ def ]phenanthren-4-one”
    Metallinos, C.; Dudding, T.; Zaifman, J.; Chaytor, J. L.; Taylor, N. J.
    J. Org. Chem. 2007, 72(3), 957-963.
  4. “Phosphine triggered [3+2] allenoate-acrylate annulation: a mechanistic enlightenment” Mercier, E., Fonovic, B., Henry,C., Kwon, O., Dudding, T. Tetrahedron Lett. 2007, 48(20), 3617-3620.
  5. “Hydrogen Bonding Catalysis Operates by Charge Stabilization in Highly Polar Diels-Alder Reactions” Gordillo, R.; Dudding, T.; Anderson, C. D.; Houk, K. N. Org. Lett. 2007, 9(3), 501-503.
  6. “A Mechanistic Study  on the Catalytic, Asymmetric a-Bromination of Acid Chlorides” Dogo-Isonagie, C; Bekele, T.; France, S.; Wolfer, S.; Weatherwax, A.; Taggi, A. E.; Paull, D. H.; Dudding, T.; Lectka, T. Eur. J. Org. Chem. 2007, 7, 1091-1100.
  7.  “Trypsin-Catalyzed-Triethoxysilyl-Terminated Polydimethylsiloxane: An ω,αCross-Linking of Experimental and Computational Approach” Zelisko, P. M; Dudding, T; Arnelien, K. R.; Stanisic, H, Clarson, S. J.; Fitzgerald, J.; Owen, M.; Smith, S.; Van Dyke, ME Eds., Polymer Preprints 2007, 48(2), 984
  8.  “Theoretical Rationale for Regioselection in Phosphine-Catalyzed Allenoate Additions to Acrylates, Imines, and Aldehydes” Dudding, T.; Kwon, O.; Mercier, E., Org. Lett. 2006, 8(17), 3643-3646.
  9. “Phosphine-Catalyzed Synthesis of 1,3-Dioxan-4-ylidenes” Zhu, X.-F.; Henry, C. E.; Wang, J.; Dudding, T.; Kwon, O., Org. Lett. 2005, 7(7), 1387-1390.
  10. “Computational Predictions of Stereochemistry in Asymmetric Thiazolium and Triazolium Catalyzed Benzoin Condensations” Dudding, T.; Houk, K. N. Proc. Natl. Acad. Sci. USA 2004, 101, 5770-5775.
  11. “A Multistage, One-Pot Procedure Mediated by a Single Catalyst:  A New -Amino Acids” Hafez, A. M.;bApproach to the Catalytic Asymmetric Synthesis of  Dudding, T.; Wagerle, T. R.; Shah, M. H.; Taggi, A. E.; Lectka, T. J. Org. Chem. 2003, 68, 5819-5825.
  12. “Molecular Mechanics Calculations as Predictors of Enantioselectivity for Chiral Nucleophile Catalyzed Reactions” Taggi, A. E.; Hafez, A. M.; Dudding, T.; Lectka, T. Tetrahedron 2002, 58, 8351-8356.
  13. “A Structure-Activity Study of Spermicidal and anti-HIV properties of Hydroxylated Cationic Surfactants” Wong, Yue Ling; Hubieki, M.; Curfman, C. L.; Doncel, G. F.; Dudding, T. C.; Savle, P. S.; Gandour, R. D. Bioorg. Med. Chem. 2002, 10, 3599-3608.
  14. “A Catalyst that Plays Multiple Roles:  Asymmetric Synthesis of alpha-Substituted Aspartic Acid Derivatives through a Four-Stage, One-Pot Procedure” Dudding, T.; Hafez, A. M.; Taggi, A. E.; Wagerle, T. R.; Lectka, T. Org. Lett. 2002, 4, 387-390.
  15. "Catalytic, Enantioselective Alkylation of alpha-Imino Esters Derivatives” Ferraris, D.; Young, B.; Cox, C.; Dudding, T.; Drury, W.J. III; Ryzhkov, L.; Taggi, A. E.; Lectka, T . J. Am. Chem. Soc.   2002, 124, 67-77.
  16. “Spermicidal, Anti-HIV, and Micellar Properties of Di- and Trihydroxylated Cationic Surfactants” Wong, Yue-Ling; Curfman, C. L.; Doncel, G. F.; Hubieki, M. P.; Dudding, T. C.; Savle, P. S.; Gandour, R. D. Tetrahedron 2002, 58, 45-54.
  17. “Asymmetric Catalysis on Sequentially-linked Columns” Hafez, A. M.; Taggi, A. E.; Dudding, T.; Lectka, T. J. Am. Chem. Soc. 2001, 123, 10853-10859.
  18. “Base- and Acid-catalyzed Interconversions of O-acyl- and N-acyl-ethanolamines:  A Cautionary Note for Lipid Analysis” Markey, S. P.; Dudding, T.; Wang, Tao-Chin L. J. Lipid Res. 2000, 41, 657-662.  
  19. "Catalytic, Enantioselective Alkylation of N,O- and N,N-Acetals and Hemiacetals"  Ferraris, D.;     Young, B.; Dudding, T.; Drury, W. J. III; Lectka, T. Tetrahedron 1999, 55, 8869-8882.
  20. "Catalytic Enantioselective Alkylation Reactions of N,O-Acetals" Ferraris, D.; Young,B.; Dudding, T.; Drury, W. J. III; Lectka, T.  J. Org. Chem. 1999, 64, 2168-2169.
  21. "Diastereo- and Enantioselective Alkylation of alpha-Imino Esters with Cyclic Enol Silanes Catalyzed by (R)-Tol-BINAP-CuClO4•(MeCN)2" Ferraris, D.; Young, B.; Cox, C.; Drury, W. J. III; Dudding, T.; Lectka, T. J. Org. Chem. 1998, 63, 6090-6091.
  22. "Catalytic, Enantioselective Alkylation of alpha-Imino Esters Using Late Transition Metal Phosphine Complexes as Catalysts" Ferraris, D.; Young, B.; Dudding, T.; Lectka, T. J. Am. Chem. Soc. 1998, 120, 4548-4549.
  23. "Use of pH-Zone-Refining Countercurrent Chromatography to Separate 2- and 6-Nitro-4-Chloro-Methoxybenzoic Acid" Dudding, T. C.; Mekonnen B.; Ito,Y.; Ziffer, H. J. Liq. Chromatogr Relat. Technol. 1998, 21, 195-201.
  24. "Oxidation of 2-Methoxynaphthlene by Toluene, Naphthalene and Biphenyl Dioxygenases:  Structure and Absolute Stereochemistry of Metabolites" Whited, G. M.; Downie, J. C.; Hudlicky, T.; Fearnley, S. P.; Dudding, T. C.; Oliva, H. F.; Parker, D. Bioorg. Med. Chem. 1994, 2, 727-734.
  25. "Microbial Oxidation of Aromatics in Enantiocontrolled Synthesis.  Part 1.  Expedient and General Asymmetric Synthesis of Inositols and Carbohydrates via an Unusual Oxidation of a Polarized Diene with Potassium Permanganate" Hudlicky, T.; Mandel, M.; Rouden, J.; Lee, R. S.; Bachmann, B.; Dudding, T. C.; Yost, K. J.; Merols, J. S. J. Chem. Soc., Perkin Trans. 1 1994, 2, 1553-1567.

POSTAL ADDRESS

Dept. of Chemistry
Brock University
500 Glenridge Ave.
St. Catharines, ON
Canada, L2S 3A1
Tel: (905) 688-5550 x3406
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cskorski@brocku.ca
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