Publications

Department of Chemistry




Publications

 

Chapters in Books and Patents:
 
Metallinos, C.; Stromski, K., “Other Stoichiometric Metalation Reactions of Pyridines, Quinolines and Isoquinolines: Ate Bases and their Alkali Metal Salt-Modified Congeners” in Topics in Heterocyclic Chemistry; Schnürch, M. (Ed.), Springer, 2012, in press.
 
Metallinos, C., “Method for Preparing Ortho-Substituted Aminoferrocenes”, United States Patent 7,982,064, July 19, 2011.
 
Deng, W.-P.; Snieckus, V.; Metallinos, C., "Stereoselective Synthesis of Planar
Chiral Ferrocenes" in Chiral Ferrocenes in Asymmetric Catalysis: Synthesis and Applications; Dai, L.-X.; Hou, X.-L. (Eds.), Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim, Germany 2010, pp. 15-53.
 
Metallinos, C., "Product Class 8.1.24: Carbamoyllithium and Trihalomethyllithium Compounds" in Science of Synthesis, Vol. 8a; Majewski, M.; Snieckus, V. (Eds.), Georg Thieme-Verlag KG: Stuttgart, Germany 2006, pp. 795-804.
 
 
Journal Papers:
 
Metallinos, C.; John, J.; Zaifman, J.; Emberson, K. “Diastereoselective Synthesis of N-Substituted Planar Chiral Ferrocenes Using a Proline Hydantoin-Derived Auxiliary”, Adv. Synth. Catal. 2012, 354, 602-606.
 
Metallinos, C.; Van Belle, L., "Asymmetric Hydrogenation of Alkenes with Planar Chiral 2-Phosphino-1-Aminoferrocene-Iridium(I) Complexes" (invited paper), J. Organomet. Chem. 2011, 696, 141-149.
 
Metallinos, C.; Zaifman, J.; Dudding, T.; Van Belle, L.; Taban, K., "Asymmetric Lithiation of Boron Trifluoride-Activated Aminoferrocenes: An Experimental and Computational Investigation", Adv. Synth. Catal. 2010, 352, 1967-1982.
 
Metallinos, C.; Xu, S., "Stereoselective Synthesis of 5-Substituted Pyrrolo[1,2c]imidazol-3-ones: Access to Annulated Chiral Imidazol(in)ium Salts", Org. Lett. 2010, 12, 76-79.
 
Metallinos, C.; Zaifman, J.; Van Belle, L.; Dodge, L.; Pilkington, M., "Palladium(II), Platinum(II) and Iridium(I) Complexes of 2-Phosphino-1-dimethylaminoferrocenes: A Survey of Structure and Catalysis", Organometallics 2009, 28, 4534-4543.
 
Metallinos, C.; Du, X. "Neutral and Cationic Iridium(I) Complexes Bearing Chiral Phenanthroline-Derived Benzimidazolylidenes: Synthetic, Structural and Catalytic Studies", Organometallics 2009, 28, 1233-1242.
 
Metallinos, C.; Zaifman, J.; Dodge, L., "Aminoferrocene Lithiation by Boron Trifluoride Activation", Org. Lett. 2008, 10, 3527-3530.
 
Metallinos, C.; Barrett, F. B.; Xu, S., "Brønsted Acid Catalyzed Asymmetric Reduction of 2- and 2,9-Substituted 1,10-Phenanthrolines", Synlett 2008, 720-724.
 
Blanchet, J.; Macklin, T.; Ang, P.; Metallinos, C.; Snieckus, V., "Directed ortho Metalation-Cross Coupling Strategies. N-Cumyl Arylsulfonamides. Facile Deprotection and Expedient Route to 4- and 4,7-Substituted Saccharins", J. Org. Chem. 2007, 72, 3199-3206.
 
Metallinos, C.; Dudding, T; Zaifman, J.; Chaytor, J. L.; Taylor, N. J., "An Experimental and Theoretical Study of the Asymmetric Lithiation of 1,2,3,5,6,7-Hexahydro-3a,4a-diazacyclopenta[def]phenanthren-4-one", J. Org. Chem. 2007, 72, 957-963.
 
Metallinos, C.; Barrett, F. B.; Wang, Y.; Xu, S.; Taylor, N. J., "Reduction of Substituted 1,10-Phenanthrolines as a Route to Rigid Chiral Benzimidazolylidenes", Tetrahedron 2006, 62, 11145-11157.
 
Metallinos, C.; Tremblay, D. T.; Barrett, F. B.; Taylor, N. J., "1,1′-Bis(phosphoranylidenamino)ferrocene Palladium(II) Complexes: An Unusual Case of Dative Fe → Pd Bonding", J. Organomet. Chem. 2006, 691, 2044-2047.
 
Metallinos, C.; Barrett, F. B.; Chaytor, J. L.; Heska, M. E. A.,"A Benzimidazole-Based N-Heterocyclic Carbene Derived from 1,10-Phenanthroline", Org. Lett. 2004, 6, 3641-3644.
 
Beierle, J. M.; Osimboni, E. B.; Metallinos, C.; Zhao, Y.; Kelly, T. R., "Synthesis of Louisianin C", J. Org. Chem. 2003, 68, 4970-4972.
 
Metallinos, C.; Szillat, H.; Taylor, N. J.; Snieckus, V., "(—)-Sparteine-Mediated Directed ortho Metalation of N-Cumyl-N-Ethyl Ferrocenecarboxamide. Versatile Routes to Planar Chiral Ferrocenecarboxamides, Amines, Esters and Phosphines", Adv. Synth. Catal. 2003, 345, 370-382.
 
Metallinos, C., "The N-Cumyl Group for Facile Manipulation of Carboxamides, Sulfonamides and Aryl O-Carbamates Post-Directed ortho Metalation", Synlett 2002, 1556-1557.
 
Metallinos C.; Snieckus, V., "(—)-Sparteine-Mediated Metalation of Ferrocenesulfonates. The First Case of Double Asymmetric Induction of Ferrocene Planar Chirality", Org. Lett. 2002, 4, 1935-1938.
 
Metallinos, C.; Nerdinger, S.; Snieckus, V., "N-Cumyl Benzamide, Sulfonamide and Aryl O-Carbamate Directed Metalation Groups. Mild Hydrolytic Lability for Facile Manipulation of Directed ortho Metalation-Derived Aromatics", Org. Lett. 1999, 1, 1183-1186.
 
 
Invited Talks:
 
Metallinos, C., “Proline Congeners in the Stereoselective Synthesis of Chiral Imidazolylidenes and N-Substituted Ferrocenes”, 14th Blue Danube Symposia on Heterocyclic Chemistry, Podbanske, Slovakia, June 26-29, 2011.
 
Metallinos, C., Alphora Research Inc., Oakville, ON, January 27, 2011.
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Department of Chemistry, University of York, March 9, 2010, Heslington, York, UK.
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Department of Organic and Nuclear Chemistry, Charles University, May 4, 2010, Prague, Czech Republic.
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Institute for Organic Chemistry, University of Regensburg, May 10, 2010, Regensburg, Germany.
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, May 20, 2010, Münster, Germany.
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Department of Chemistry, University of Ioannina, May 27, 2010, Ioannina, Greece.
 
Metallinos C, " Annulated Chiral NHCs Derived from Phenanthrolines and Pyrroloimidazol(in)-3-ones", 93rd CSC Conference and Exhibition, Toronto, ON, May 29-June 2, 2010 (declined due to conflict).
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Department of Chemistry, University of Athens, June 21, 2010, Athens, Greece.
 
Metallinos, C., "Annulated Chiral NHCs Derived from Phenanthrolines and Pyrroloimidazol(in)-3-ones", ACS Northeast Regional Meeting (NERM), Oct. 7-10, 2009, Hartford, CT, USA.
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Department of Chemistry, University of Western Ontario, Sept. 23, 2009.
 
Metallinos C., "Annulated Chiral NHCs Derived from Phenanthrolines and Pyrroloimidazol(in)-3-ones", 22nd International Conference on Heterocyclic Chemistry (ICHC-22), Aug. 2-7, 2009, St. John's, NL.
 
Metallinos, C., "Design, Synthesis and Applications of Chiral N-Heterocyclic and Organometallic Reagents", Department of Chemistry and Biochemistry, University of Windsor, April 3, 2009.
 
Metallinos, C., "Reduced Heterocycles in the Synthesis of Benzimidazolylidenes and Aminoferrocenes", Queen's University, Oct. 22, 2007, Kingston, ON, Canada.
 
Metallinos, C., "Reduced Heterocycles in the Synthesis of Benzimidazolylidenes and Aminoferrocenes", Yeditepe University, June 12, 2007, Istanbul, Turkey.
 
Metallinos, C., "Partially Reduced Heterocycles in the Synthesis of Benzimidazolylidenes and Aminoferrocenes", Université de Montréal, April 19, 2007, Montreal, QC, Canada.
 
Metallinos, C., "Partially Reduced Heterocycles in the Synthesis of Benzimidazolylidenes and Aminoferrocenes", Ontario University Institute of Technology, April 16, 2007, Oshawa, ON, Canada.
 
Metallinos, C., "Reduction of Substituted Phenanthrolines as a Route to Chiral Benzimidazolylidenes", 8th Organic Workshop for Leading, Young Canadian Chemists, May 23-26, 2006, White Point Beach, NS, Canada.

POSTAL ADDRESS
Dept. of Chemistry
Brock University
500 Glenridge Ave.
St. Catharines, ON
Canada, L2S 3A1
Tel: (905) 688-5550 x3406

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Marie Harris
mharris@brocku.ca

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