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C. Skorski,
Admininstrative Assistant
Dept. of Chemistry
Brock University
500 Glenridge Ave.
St. Catharines, ON
Canada, L2S 3A1
Tel: (905) 688-5550 x3406
Fax: (905) 682-9020
E-mail: cskorski@brocku.ca


Tomas Hudlicky: Publications
All articles available upon request from Prof. Hudlicky

Papers in refereed journals
(principal author in boldface) (* denotes publications by invitation)

  1. Reactions of dialkali salts of benzoylacetone with 2-chloroquinoline. Evidence for an SRN1 mechanism in heteroaromatic nucleophilic substitution. Wolfe, J. F.; Greene, J. C.; Hudlicky, T. J. Org. Chem. 1972, 37, 3199.
  2. Selective C-alkylation of phenyl-acetylureas through 1,3,5-trialkali salt intermediates. Taylor, J. D.; Trimitsis, G. B.; Hudlicky, T.; Wolfe, J. F. J. Org. Chem. 1973, 38, 1236.
  3. The SRN1 mechanism in heteroaromatic nucleophilic substitution. Photostimulation and entrainment of the reaction of lithioacetone with 2-chloroquinoline. Hay, J. V.; Hudlicky, T.; Wolfe, J. F. J. Am. Chem. Soc. 1975, 97, 374.
  4. Reactions of isatin dimethyl ketal and its ethyl imino ether with methyllithium. Wenkert, E.; Hudlicky, T. Synth. Commun. 1977, 7, 541.
  5. Short synthesis of eburnamonine via ß-oxycyclo-propylcarbonyl and related intermediates. Wenkert, E.; Hudlicky, T.; Showalter, H. J. Am. Chem. Soc. 1978, 100, 4893.
  6. The total synthesis of (±)-isocomene by an intramolecular ene reaction. Oppolzer, W.; Battig, K.; Hudlicky, T. Helv. Chim. Acta 1979, 62, 1493.
  7. Synthesis of dienic acids. Application of the Arndt-Eistert reaction to unsaturated diazoketones. Hudlicky, T.; Sheth, J. P. Tetrahedron Lett. 1979, 20, 2667.
  8. Intramolecular carbenoid addition to 1,3-dienes. Synthesis of cyclopentene annulated ring systems. Hudlicky, T.; Sheth, J. P.; Gee, V.; Barnvos, D. Tetrahedron Lett. 1979, 20, 4889.
  9. Total synthesis of (±)-filifolone. Hudlicky, T.; Kutchan, T. Tetrahedron Lett. 1980, 21, 691. 
  10. Total synthesis of (±)-hirsutene. Hudlicky, T.; Kutchan, T. M.; Wilson, S. R.; Mao, D. T. J. Am. Chem. Soc.1980, 102, 6351.
  11. Selectivity in retro-ene vs. cyclopentene rearrangements of cis-methylvinylcyclopropane. Hudlicky, T.; Koszyk, F. J. Tetrahedron Lett. 1980, 21, 2487.
  12. Cyclopentene annulation via intra-molecular addition of diazo ketones to 1,3-dienes. Applications to the synthesis of cyclopentanoid terpenes. Hudlicky, T.; Koszyk, F. J.; Kutchan, T. M.; Sheth, J. P. J. Org. Chem. 1980, 45, 5020.
  13. Improved synthesis and characterization of Pictet–Spengler adducts of phenylpyruvic acid and biogenic amines. Hudlicky, T.; Kutchan, T. M.; Shen, G.; Sutliff, V.; Coscia, C. J. J. Org. Chem. 1981, 46, 1738.
  14. Intramolecular cyclopentene annulation. 2. Synthesis and carbon-13 nuclear magnetic resonance spectroscopy of bicyclo[4.3.0]-non-7-en-2-ones. Hudlicky, T.; Koszyk, F. J.; Dochwat, D. M.; Cantrell, G. C. J. Org. Chem. 1981, 46, 2911.
  15. * A total synthesis of (±)-isocomene and (±) ß-isocomene by an intramolecular ene reaction. Oppolzer, W.; Battig, K.; Hudlicky, T. Tetrahedron lett. 1981, 37, 4359.
  16. Aluminum oxide catalyzed isomerization of acylated cycloalkenes. Hudlicky, T.; Srnak, T. Tetrahedron Lett. 1981, 22, 3351.
  17. Terpenic acids by cyclopentane annulation of exocyclic dienes. Synthesis of triquinane portion of retigeranic acid. Hudlicky, T.; Short, R. P. J. Org. Chem. 1982, 47, 1522.
  18. Synthesis of homoharringtonine and its derivative by partial esterification of cephalotaxine. Hiranuma, S.; Hudlicky, T. Tetrahedron Lett. 1982, 23, 3431.
  19. Two topologically distinct total syntheses of (±)-sarkomycin. Govindan, S. V.; Hudlicky, T.; Koszyk, F. J. J. Org. Chem. 1983, 48, 3581.
  20. General method of synthesis of cyclopentanoid terpenic acids. Stereocontrolled total syntheses of (±)-isocomenic acid and (±)-epiisocomenic acid. Short, R. P.; Ranu, B. C.; Revol, J. M.; Hudlicky, T. J. Org. Chem. 1983, 48, 4453.
  21. Intramolecular cyclopentene annulation. 3. Synthesis and carbon-13 nuclear magnetic resonance spectroscopy of bicyclic cyclopentene lactones as potential perhydroazulene and/or monoterpene synthons. Hudlicky, T.; Govindan, S. V.; Reddy, D. B.; Kulp, T.; Still, B.; Sheth, J. P. J. Org. Chem. 1983, 48, 3422.
  22. Studies in Cephalotaxus alkaloids. Stereospecific total synthesis of homoharringtonine. Hiranuma, S.; Shibata, M.; Hudlicky, T. J. Org. Chem. 1983, 48, 5321.
  23. Regioselectivity in the Reformatsky reaction of 4-bromocrotonate. Role of the catalyst and the solvent in the normal vs. abnormal modes of addition to carbonyl substrates. Hudlicky, T.; Rice, L.; Boston, C.; Finklea, H.; Frazier, J.; Suder, B. J. Org. Chem. 1984, 49, 1845.
  24. Stereocontrolled total synthesis of isocomene sesquiterpenes. Higgs, L.; Kavka, M.; Ranu, B. C.; Hudlicky, T. Tetrahedron Lett. 1984, 25, 2447.
  25. Intramolecular Simmons–Smith reaction and other synthetic alternatives to cyclopropanation of dienic diazoketones. Parallel decomposition pathways of a sterically congested diazoketone and its vinylcyclopropane under thermal, photolytic, acid-catalyzed and radical release conditions. Hudlicky, T.; Ranu, B. C.; Naqvi, S.M.; Srnak, A. J. Org. Chem. 1985, 50, 123.
  26. Intramolecular [4+1] pyrroline annulation approach to pyrrolizidine alkaloids. Formal total synthesis of (±)-supinidine. Hudlicky, T.; Frazier, J. O.; Kwart, L. D. Tetrahedron Lett. 1985, 26, 3523.
  27. Heteroatom cyclopentene annulation. Synthesis of a guaiane ring system. Hudlicky, T.; Govindan, S. V.; Frazier, J. O. J. Org. Chem. 1985, 50, 4166.
  28. Studies in the regioselectivity of the vinylogous Reformatsky reaction with ambident electrophiles: Reversibility, mechanism, and synthetic utility. Hudlicky, T.; Natchus, M. G.; Kwart, L. D.; Colwell, B. J. Org. Chem. 1985, 50, 4300.
  29. Claisen/ozonolysis alternative to alkylation of enolate anions. Synthesis of 1,4-dicarbonyl compounds. Hudlicky, T.; Carman, W. L.; Kwart, L. D. Synth. Commun.1986, 16, 169.
  30. Total synthesis of (±)-epiisocomenes by hydrogenation of "Chaterjee's Ketone." Kwart, L.D.; Tiedje, M.; Frazier, J. O.; Hudlicky, T. Synth. Commun. 1986, 16, 393.
  31. Topological selectivity in the intramolecular [4+1] pyrroline annulation. Formal total stereospecific synthesis of (±)-supinidine, (±)-isoretronecanol and (±)-trachelanthamidine. Hudlicky, T.; Seoane, G.; Seoane, A.; Frazier, J. O.; Kwart, L. D.; Tiedje, M. H.; Beal, C. J. Am. Chem. Soc. 1986, 108, 3755.
  32. * General methodology for the topologically selective preparation of linear and nonlinear tricyclopentanoids of hirsutane and isocomene type via a Claisen rearrangement/cyclopentene annulation sequence. Total synthesis of (±)-epiisocomene. Hudlicky, T.; Kwart, L.D.; Tiedje, M.H.; Ranu, B.C.; Short, R.P.; Frazier, J.O. Rigby, H.L. Synthesis 1986, 716.
  33. New vinylcyclopropanation methodology and reagents for potential for [2+3] cyclopentene, dihydrofuran, and pyrroline annulations. Hudlicky, T.; Radesca, L.; Luna, H.; Anderson, F.E. J. Org. Chem. 1986, 51, 4746.
  34. [2+3] Cyclopentene annulation and other trimethylsilyl iodide-mediated rearrangement pathways of vinylcyclopropanes. Fleming, A.; Sinai–Zingde, G.; Natchus, M.; Hudlicky, T. Tetrahedron Lett. 1987, 28, 167.
  35. Mild methodology for [4+1] pyrroline annulation. Second generation synthesis of pyrrolizidine alkaloids. Hudlicky, T.; Sinai–Zingde, G.; Seoane, G. Synth. Commun.1987, 17, 1155.
  36. Menthyl 2-bromocrotonate and menthyl 4-bromo-crotonate: Reagents for chiral vinylogous Darzen and Reformatsky reactions. Hudlicky, T.; Radesca, L.; Rigby, H. L. J. Org. Chem. 1987, 52, 4397.
  37. General method of synthesis for natural long-chain ß-diketones. Barbieri, G.; Seoane, G.; Trabazo, J.; Riva, A.; Umpierrez, F.; Radesca, L.; Tubio, R.; Hudlicky, T.; Kwart, L. D. J. Nat. Prod. 1987, 50, 646.
  38. Stereocontrolled total synthesis of pentalenenes via [2+3] and [4+1] cyclopentene annulation methodologies. Hudlicky, T.; Natchus, M. G.; Sinai–Zingde, G. J. Org. Chem.1987, 52, 4641.
  39. * System oriented design of triquinanes: Stereocontrolled synthesis of pentalenic acid and pentalenene. Hudlicky, T.; Sinai–Zingde, G.; Natchus, M. G.; Ranu, B. C.; Papadopoulos, P. Tetrahedron 1987, 43, 5685.
  40. Selective reduction of α,ß-unsaturated esters in the presence of olefins. Hudlicky, T.; Sinai–Zingde, G.; Natchus, M. G. Tetrahedron Lett. 1987, 28, 5287.
  41. Synthesis of eburnamonine and dehydroaspidospermidine. Wenkert, E.; Hudlicky, T. J. Org. Chem. 1988, 53, 1953.
  42. Intramolecular [4+1] pyrroline annulation via azide–diene cycloadditions. 2. Formal stereoselective total synthesis of (±)-platynecine, (±)-hastanecine, (±)-turneforcidine, and (±)-dihydroxyheliotridane. Hudlicky, T.; Seoane, G.; Lovelace, T. C. J. Org. Chem. 1988, 53, 2094.
  43. * Enantioselective synthesis through microbial oxidation of arenes. 1. Efficient preparation of terpene and prostanoid synthons. Hudlicky, T.; Luna, H.; Barbieri, G.; Kwart, L. D. J. Am. Chem. Soc. 1988, 110, 4735.
  44. Short enantioselective synthesis of (–)-retigeranic acid via [2+3] annulation. Hudlicky, T.; Radesca–Kwart; L.; Li, L.; Bryant, T. Tetrahedron Lett. 1988, 29, 3283.
  45. 4,4-Dimethyl-2-cyclopenten-1-one (2-cyclopenten-1-one, 4,4-dimethyl-). Anderson III, F.; Pauley, D. O.; Hudlicky, T. Org. Synth. 1988, 67, 121.
  46. 3-Hydroxy-1-cyclohexene-1-carboxaldehyde (l-cyclohexene-1-carboxaldehyde, 3-hydroxy-). Rigby, H. L.; Neveu, M.; Pauley, D.; Ranu, B. C.; Hudlicky, T. Org. Synth. 1988, 67, 205.
  47. * [2+3] Dihydrofuran annulation via vinyloxiranation of carbonyl compounds. Application to total synthesis of polyfuranoid natural products. Hudlicky, T.; Fleming, A.; Lovelace, T. C. Tetrahedron 1989, 45, 3037.
  48. [2+3] and [3+4] annulation of enones. Enantiocontrolled total synthesis of (–)-retigeranic acid. Hudlicky, T.; Fleming, A.; Radesca, L. J. Am. Chem. Soc. 1989, 111, 6691.
  49. Enantioselective synthesis of (–)-zeylena from styrene. Hudlicky, T.; Seoane, G.; Pettus, T. J. Org. Chem. 1989, 54, 4239.
  50. An enantiodivergent approach to D- and L-erythrose via microbial oxidation of chlorobenzene. Hudlicky, T.; Luna, H.; Price, J. D.; Rulin, F. Tetrahedron Lett. 1989, 30, 4053.
  51. A Michael alternative to cyclopentene annulations. Hudlicky, T.; Maxwell, M. Synth. Commun. 1989, 19, 1847.
  52. Tin analogs of the vinylogous Reformatsky reaction. Regio- and stereochemical considerations. Fan, R.; Hudlicky, T. Tetrahedron Lett. 1989, 30, 5533.
  53. Microbial oxidation of naphthalene derivatives. Absolute configuration of metabolites. Deluca, M.; Hudlicky, T. Tetrahedron Lett. 1990, 31, 13.
  54. * Microbial oxidation of chloroaromatics in enantioselective synthesis of carbohydrates: L-ribonic-g-lactone. Hudlicky, T.; Price, J. D. Synlett 1990, 159.
  55. 4-Siloxy-a-bromocrotonate: A new reagent for [2+3] annulation leading to oxygenated cyclopentenes at low temperatures. Hudlicky, T.; Heard, N. E.; Fleming, A. J. Org. Chem. 1990, 55, 2570.
  56. * Microbial oxidation of chloroaromatics in the enantiocontrolled synthesis of cyclitols: (–)-dihydroconduritol C. Hudlicky, T.; Price, J. D.; Luna, H.; Andersen, C. Synlett 1990, 309.
  57. Practical synthesis of vinylcyclopropane. Hudlicky, T.; Tsunoda, T. Synlett 1990, 322.
  58. Microbial oxidation of chloroaromatics in the enantiodivergent synthesis of pyrrolizidine alkaloids: trihydroxyheliotridanes. Hudlicky, T.; Luna, H.; Price, J. D.; Rulin, F. J. Org. Chem. 1990, 55, 4683.
  59. Synthesis of ß-methoxy enones via a new two-carbon extension of carboxylic acids. Hudlicky, T.; Olivo, H. F.; Natchus, M. G.; Umpierrez, E. F.; Pandolfi, E.; Volonterio, C. J. Org. Chem. 1990, 55, 4767.
  60. * An overview of the total synthesis of pyrrolizidine alkaloids via [4+1] azide–diene annulation methodology. Hudlicky, T.; Seoane, G.; Price, J. D.; Gadamasetti, K. (in part). Synlett 1990, 433.
  61. Formal total synthesis of ipomeamarone via the [2+3] dihydrofuran annulation. Hudlicky, T.; Lovelace, T. C. Synth. Commun. 1990, 20, 1721.
  62. Efficient and enantiodivergent synthesis of (+)- and (–)-pinitol. Hudlicky, T.; Rulin, F.; Tsunoda, T.; Price, J. D. J. Am. Chem. Soc. 1990, 112, 9439.
  63. Yeast-mediated resolution of ß-keto esters of prochiral alcohols. Hudlicky, T.; Gadamasetti, K. G.; Tsunoda, T.; Murry, J. A.; Keck, G. E. J. Org. Chem. 1991, 56, 3619.
  64. A new [2+3] annulation for highly functionalized dihydrofurans via C–C bond formation. Hudlicky, T.; Barbieri, G. J. Org. Chem. 1991, 56, 4598.
  65. Enantiocontrolled total synthesis of conduritols. (+)-conduritol E and (–)-conduritol F. Hudlicky, T.; Price, J. D.; Olivo, H. F. Synlett 1991, 645.
  66. Stereospecific synthesis of aminocyclitols via cycloadditions of unsymetrical optically pure dienes: conduramine A-1 and dihydroconduramine A-1. Hudlicky, T.; Olivo, H. F. Tetrahedron Lett. 1991, 32, 6077.
  67. * Biocatalysis as a strategy of choice in the exhaustive enantiomerically controlled synthesis of conduritols. Hudlicky, T.; Luna, H.; Olivo, H.F.; Andersen, C.; Nugent, T.; Price, J. D. J. Chem. Soc. Perkin Trans. 1 1991, 2907.
  68. * Biocatalysis as a rational approach to enantiodivergent synthesis of highly oxygenated compounds: (+)- and (–)-pinitol and other cyclitols. Hudlicky, T.; Rulin, F.; Tsunoda, T.; Luna, H.; Andersen, C.; Price, J. D. Isr. J. Chem. 1991, 31, 229.
  69. * A model study directed towards a practical enantioselective total synthesis of (–)-morphine. Hudlicky, T.; Boros, C. H.; Boros, E. E. Synthesis 1992, 174.
  70. Improved practical synthesis of a prostaglandin and carbocyclic nucleoside synthon. Hudlicky, T.; Natchus, M. G.; Nugent, T. Synth. Commun. 1992, 22, 151.
  71. Stereoselective dimerizations of arene cis-diol acetonides derived from the oxidation of halobenzenes by Pseudomonas putida: Absolute configuration of the adducts by x-ray crystallography. Hudlicky, T.; Boros, E. E.; Olivo, H. F.; Merola, J. S. J. Org. Chem. 1992, 57, 1026.
  72. * Palladium-catalyzed coupling of terminal alkynes to the free cis-diol metabolite produced from the oxidation of bromobenzene by Pseudomonas putida: Synthesis of new homochiral 3-alkynyl-cis-cyclohexa-3,5-diene-1,2-diols. Hudlicky, T.; Boros, E. E. Tetrahedron: Asymmetry 1992, 3, 217.
  73. Homochiral amine synthesis by baker's yeast resolution of a ß-keto amide: 1-phenylethylamine. Hudlicky, T.; Gillman, G.; Andersen, C. Tetrahedron: Asymmetry 1992, 3, 281.
  74. Selectivity in [2+3] and [4+3] annulations. Cope rearrangement of (silyloxy)divinylcyclopropane systems leading to functionalized bicyclo[3.2.n]alkenyl derivatives. Hudlicky, T.; Nguyen, B. V. J. Org. Chem. 1992, 57, 1933.
  75. Microbial oxidation of o-chlorostyrene: Determination of absolute stereochemistry of the cis-diol metabolite by a convergent synthesis utilizing an intramolecular Diels–Alder reaction. Hudlicky, T.; Boros, E. E.; Boros, C. H. Synlett 1992, 391.
  76. Chemoenzymatic enantiocontrolled synthesis of (–)-specionin. Hudlicky, T.; Natchus, M. G. J. Org. Chem. 1992, 57, 4740.
  77. Practical preparation of some potentially anesthetic fluoroalkanes: regiocontolled introduction of hydrogen atoms. Hudlicky, T.; Fan, R.; Reed, J. W.; Carver, D. R.; Hudlicky, M.; Eger, E. I. J. Fluor. Chem. 1992, 59, 9.
  78. A short synthesis of (+)-lycoricidine. Hudlicky, T.; Olivo, H. F. J. Am. Chem. Soc. 1992, 114, 9694.
  79. Rational design of aza sugars via biocatalysis: mannojirimycin and other glycosidase inhibitors. Hudlicky, T.; Rouden, J.; Luna,. H. J. Org. Chem. 1993, 58, 985.
  80. Unusual oxidation of 1-halo-1,3-dienes with permanganate. Expedient syntheses of (+)-D-chiro-3-inosose and (+)-D-chiro-inositol from chlorobenzene. Mandel, M.; Hudlicky,T.; Kwart, L. D.; Whited, G. M. J. Org. Chem. 1993, 58, 2331.
  81. General synthesis of inositols by hydrolysis of conduritol epoxides obtained biocatalytically from halogenobenzenes: (+)-D-chiro-inositol, allo-inositol, muco-inositol, and neo-inositol. Mandel, M.; Hudlicky, T. J. Chem. Soc. Perkin Trans. 1 1993, 741.
  82. New Diels–Alder dimers of (1S, 2R)-cis-1,2-isopropylidene-dioxy-3-ethenylcyclohexa-3,5-diene. Hudlicky, T.; Boros, C. H. Tetrahedron Lett. 1993, 34, 2557.
  83. Total synthesis of (+)-kifunensine, a potent glycosidase inhibitor. Rouden, J.; Hudlicky, T. J. Chem. Soc. Perkin 1 1993, 1095.
  84. Conduritol-halo epoxides: versatile synthons for cyclitol synthesis. Mandel, M.; Hudlicky, T. Synlett 1993, 418.
  85. * New diol metabolites derived by biooxidation of chlorostyrenes with Pseudomonas putida: determination of absolute stereochemistry and enantiomeric excess by convergent syntheses. Hudlicky, T.; Boros, E. E.; Boros, C. H. Tetrahedron: Asymmetry 1993, 4, 1365.
  86. From chlorobenzene to a carbohydrate in two steps. A new chemoenzymatic synthesis of 2,3-0-isopropylidene-D-erythruronolactone. Mandel, M.; Hudlicky, T.; Kwart, L. D.; Whited, G. M. Collect. Czech. Chem. Commun. 1993, 58, 2517.
  87. Microbial oxidation of 2-bromostyrene by Psuedomonas putida 39/D. Isolation and identification of metabolites. Königsberger, K.; Hudlicky, T. Tetrahedron: Asymmetry 1993, 4, 2469.
  88. New cycloaddition chemistry of 1-chloro-5,6-cis-isopropylidenedioxycyclohexa-1,3-diene derived from the oxidation of halogenobenzenes by Pseudomonas putida 39D. Hudlicky, T.; McKibben, B. P. J. Chem. Soc. Perkin Trans. 1 1994, 485.
  89. Microbial oxidation of aromatics in enantiocontrolled synthesis. Part 1: Expedient and general asymmetric synthesis of inositols and carbohydrates via an unusual oxidation of a polarized diene with potassium permanganate. Hudlicky, T.; Mandel, M.; Rouden, J.; Lee, R. S.; Bachmann, B.; Dudding, T.; Yost, K.; Merola, J. S. J. Chem. Soc. Perkin Trans. 1 1994, 1553.
  90. Microbial oxidation of aromatics in enantio-controlled synthesis. Part 2: Rational design of aza sugars (endo-nitrogenous). Total synthesis of (+)-kifunensine, mannojirimycin and other glycosidase inhibitors. Hudlicky, T.; Rouden, J.; Luna, H.; Allen, S. J. Am. Chem. Soc. 1994, 116, 5099.
  91. Microbial oxidation of aromatics in enantiocontrolled synthesis. Part 3: Design of amino cyclitols (exo-nitrogenous) and total synthesis of (+)-lycoricidine via acylnitrosyl cycloaddition to polarized 1-halo-1,3-cyclohexadienes. Hudlicky, T.; Olivo, H. F.; McKibben, B. J. Am. Chem. Soc. 1994, 116, 5108.
  92. Molecular properties of the "ideal" inhaled anesthetic: Studies of fluorinated methanes, ethanes, propanes and butanes. Eger, E.; Liu, J.; Koblin, D. D.; Laster, M. J.; Taheri, S.; Halsey, M. J.; Ionescu, P.; Chortkoff, B. S.; Hudlicky, T. Anesth. Analg. 1994, 79, 245.
  93. Oxa- and azabicyclo[4.1.0]heptenes as new synthons for C-disaccharide and alkaloid synthesis. Reactivity trends with carbon nucleophiles. Hudlicky, T.; Tian, X.; Königsberger, K.; Rouden, J. J. Org. Chem. 1994, 59, 4037.
  94. * Oxidation of 2-methoxynaphthalene by toluene, naphthalene, and biphenyl dioxygenases: structure and absolute stereochemistry of metabolites. Whited, G. M.; Downie, J. C.; Hudlicky, T.; Fearnley, S. P.; Olivo, H. F.; Parker, D.; Dudding, T. J. Bioorg. Med. Chem. 1994, 2, 727.
  95. Glycoconjugate coupling strategy: Synthesis of a L-chiro-inositol-gala-quercitol conjugate and the synthesis of (+)-proto-quercitol. Hudlicky, T.; Thorpe, A. J. Synlett 1994, 11, 899.
  96. Chemoenzymatic synthesis of D-erythro-C18- and L-threo-C18-sphingosines. Hudlicky, T.; Nugent, T.; Griffith, W. J. Org. Chem. 1994, 59, 7944.
  97. New chiral synthon from bromoethylbenzene: Absolute stereochemistry of a biooxidation metabolite. Stabile, M. R.; Hudlicky, T.; Meisels, M. L. Tetrahedron: Asymmetry 1995, 6, 537.
  98. First enantioselective total synthesis of (+)-pancratistatin: An unusual set of problems. Tian, X.; Hudlicky, T.; Königsberger, K. J. Am. Chem. Soc. 1995, 117, 3643.
  99. Synthesis of pseudosugars from microbial metabolites. Entwistle, D. A.; Hudlicky, T. Tetrahedron Lett. 1995, 36, 2591.
  100. Intramolecular Diels–Alder reactions of the furan diene (IMDAF); rapid construction of highly functionalized isoquinoline skeletons. Hudlicky, T.; Butora, G.; Fearnley, S. P.; Gum, A. G.; Persichini, P. J.; Stabile, M. R.; Merola, J. J. Chem. Soc. Perkin Trans. 1 1995, 2393.
  101. * The synthesis of 4-amino-4-deoxy-D-mannose and glucosamine: A new methodology for the design of homochiral amino sugars from non-carbohydrate precursors. Pitzer, K.; Hudlicky, T. Synlett 1995, 803.
  102. Unusual dehalogenation of a bridgehead halide. Biocatalytic conversion of halocyclohexadiene-cis-diols to the trans-Isomers and synthesis of optically pure cyclohexadiene-trans-diols. McKibben, B. P.; Barnosky, G. S.; Hudlicky, T. Synlett 1995, 806.
  103. * Oxidation of 2-(2-Bromoethyl)bromobenzene with toluene dioxygenase: Isolation and identification of new chiral synthons. Stabile, M. R.; Hudlicky, T.; Meisels, M. L.; Butora, G.; Gum, A. G.; Fearnley, S. P.; Thorpe, A. J.; Ellis, M. R. Chirality 1995, 7, 556.
  104. Asymmetric total synthesis of (+)-7-deoxypancaratistatin. Tian, X.; Maurya, R.; Königsberger, K.; Hudlicky, T. Synlett 1995, 1125.
  105. New chiral synthons from the microbial oxidation of bromonaphthalenes. Hudlicky, T.; Endoma, M. A.; Butora, G. Tetrahedron: Asymmetry 1996, 7, 61.
  106. Biocatalytic syntheses of protected D-mannose-d5, D-mannose-d7, D-mannitol-2,3,4,5,6-d5, and D-mannitol-1,1,2,3,4,5,6,6-d8. Hudlicky, T.; Pitzer, K. K.; Stabile, M. R.; Thorpe, A. J.; Whited, G. M. J. Org. Chem. 1996, 61, 4151.
  107. * Concise syntheses of 1,2-L-chiro-inositol conjugates and oligomers: A novel class of saccharide mimics with promising molecular properties. Hudlicky, T.; Abboud, K. A.; Bolonick, J.; Maurya, R.; Stanton, M. L.; Thorpe, A. J. J. Chem. Soc. Chem. Commun. 1996, 1717.
  108. * Toluene-dioxygenase-mediated cis-dihydroxylation of aromatics in enantioselective synthesis. Iterative glycoconjugate coupling strategy and combinatorial design for the synthesis of oligomers of nor-saccharides, inositols and pseudosugars with interesting molecular properties. Hudlicky, T.; Abboud, K. A.; Entwistle, D. A.; Fan, R.; Maurya, R.; Thorpe, A. J.; Bolonick, J.; Myers, B. Synthesis 1996, 897. [Feature Article]
  109. Nucleophilic substitution of protected ß-bromoethyl cyclohexadiene-cis-diol as an alternative to direct microbial oxidation of b-functionalized phenethyl substrates. Hudlicky, T.; Endoma, M. A.; Butora, G. J. Chem. Soc. Perkin Trans. 1, 1996, 2187.
  110. * Current status and future perspectives of cyclohexadiene-cis-diols in organic synthesis: versatile intermediates in the concise design of natural products. Hudlicky, T.; Thorpe, A. J. J. Chem. Soc. Chem. Commun. 1996, 1993. [Feature Article]
  111. Toluene-dioxygenase-mediated cis-dihydroxylation of aromatics in enantioselective synthesis. Asymmetric total syntheses of pancratistatin and 7-deoxypancratistatin, promising anti-tumor agents. Hudlicky, T.; Tian, X.; Konigsberger, K.; Maurya, R.; Rouden, J.; Fan, B. J. Am. Chem. Soc. 1996, 118, 10752.
  112. Chemoenzymatic synthesis of the morphine skeleton via radical cyclization and C10–C11 closure. Butora, G.; Hudlicky, T.; Fearnley, S. P.; Gum, A. G.; Stabile, M. R.; Abboud, K. Tetrahedron Lett. 1996, 37, 8155.
  113. Chemoenzymatic synthesis of unnatural amino acids via modified Claisen rearrangement of glycine enolates. Approach to morphine synthesis. Gonzalez, D.; Schapiro, V.; Seoane, G.; Hudlicky, T.; Abboud, K. J. Org. Chem. 1997, 62, 1194.
  114. New metabolites from toluene dioxygenase dihydroxylation of oxygenated biphenyls. Gonzalez, D.; Schapiro, V.; Seoane, G.; Hudlicky, T. Tetrahedron: Asymmetry 1997, 8, 975.
  115. Polyhydroxylated tetrahydronaphthalene ethers: Synthesis and molecular properties. Desjardins, M.; Lallemand, M.-C.; Hudlicky, T.; Abboud, K. A. Synlett 1997, 728.
  116. Regio- and stereo-chemical outcomes in the nucleophilic ring cleavage reactions of mono-epoxides derived from cis-1,2-dihydrocatechols. Banwell, M. G.; Haddad, N.; Hudlicky, T.; Nugent, T. C.; Mackay, M. F.; Richards, S. L. J. Chem. Soc. Perkin Trans. 1, 1997, 1779.
  117. * Chemoenzymatic synthesis of deoxyfluoroinositols: 5-Deoxy-5-fluoro-myo-inositol and 3-deoxy-3-fluoro-L-chiro-inositol. Nguyen, B. V.; York, C.; Hudlicky, T. Tetrahedron 1997, 53, 8807.
  118. Chemoenzymatic synthesis of fluorinated carbohydrates: 2-Deoxy-2-fluoro-D-glucose and 5-deoxy-5-fluoro-manno-g-lactol. Yan, F.; Nguyen, B. V.; York, C.; Hudlicky, T. Tetrahedron 1997, 53, 11541.
  119. Electrochemical versus anionic oxygenation of azathymine derivatives. Butora, G.; Reed, J. W.; Hudlicky, T.; Brammer, L. E., Jr.; Higgs, P. I.; Simmons, D. P.; Heard, N. E. J. Am. Chem. Soc. 1997, 119, 7694.
  120. Synthesis of conduritol, conduramine, and validoxylamine analogs from tetrahyronaphthalene-cis-diol. Lallemand, M.-C.; Desjardins, M.; Freeman, S.; Hudlicky, T. Tetrahedron Lett. 1997, 38, 7693.
  121. A practical multigram-scale synthesis of allo-inositol. Desjardins, M.; Brammer, L. E., Jr.; Hudlicky, T. Carbohydrate Res. 1997, 304, 39.
  122. Chemoenzymatic and electrochemical oxidations in the synthesis of octahydroisoquinolines for conversion to morphine. Relative merits of radical vs. acid-catalyzed cyclizations. Endoma, M. A.; Butora, G.; Claeboe, C. D.; Hudlicky, T.; Abboud, K. A. Tetrahedron Lett. 1997, 38, 8833.
  123. Chemosynthetic synthesis of all four stereoisomers of sphingosine from chlorobenzene: glycosphingolipid precursors. Nugent, T. C.; Hudlicky, T. J. Org. Chem. 1998, 63, 510.
  124. New metabolites from the microbial oxidation of fluorinated aromatic compounds. Hudlicky, T.; Gonzalez, D.; Stabile, M.; Endoma, M. A.; Deluca, M.; Parker, D.; Gibson, D.T.; Resnick, S. M.; Whited, G. M. J. Fluor. Chem. 1998, 89, 23.
  125. Advanced intramolecular Diels–Alder study toward he synthesis of (–)-morphine: Structure correction of a previously reported Diels–Alder product. Butora, G.; Gum, A. G.; Hudlicky, T.; Abboud, K. A. Synthesis 1998, 275.
  126. Toward a practical synthesis of morphine. The first several generations of a radical cyclization approach. Butora, G.; Hudlicky, T.; Fearnley, S. P.; Stabile, M. R.; Gum, A. G.; Gonzalez, D. Synthesis 1998, 665.
  127. Inositol synthesis: concise preparation of L-chiro-inositol and muco-inositol from a common intermediate. Brammer, L. E.; Hudlicky, T. Tetrahedron: Asymmetry 1998, 9, 2011.
  128. 7,8-Dihyroxy-(7R,8S,10bR)-5,6,7,8,9,10-hexahydro[1.3]oxazolo[4,3-a]isoquinolin-3-one. Abboud, K. A.; Butora, G.; Fearnley, S. P.; Gum, A. G.; Stabile, M. R.; Hudlicky, T. Acta Cryst. 1998, C54, 1162.
  129. Chemoenzymatic enantiodivergent synthesis of 1,2-dideoxy-2-amino-1-fluoro-allo-inositol. Oppong, K. A.; Hudlicky, T.; Yan, F.; York, C.; Nguyen, B. V. Tetrahedron 1999, 55, 2875.
  130. Synthesis and biological evaluation of conduritol and conduramine analogs. Desjardins, M.; Lallemand, M.-C.; Freeman, S.; Hudlicky, T.; Abboud, K. A. J. Chem. Soc. Perkin Trans. 1. 1999, 621.
  131. 1-Chloro-(2S,3S)-dihydroxycyclo-hexa-4,6-diene. Hudlicky, T.; Stabile, M.; Gibson, D. T.; Whited, G. M. Org. Synth. 1999, 76, 77.
  132. * Intramolecular N-acyliminium ion–olefin cyclization in the synthesis of optically pure isoquinoline derivatives: control of stereochemistry and application to synthesis of morphine alkaloids. Bottari, P.; Endoma, M. A. A.; Hudlicky, T.; Ghiviriga, I.; Abboud, K. A. Coll. Czech. Chem. Commun 1999, 64, 203.
  133. A short chemoenzymatic synthesis of (+)-narciclasine. Gonzalez, D.; Martinot, T.; and Hudlicky, T. Tetrahedron Lett. 1999, 40, 3081.
  134. Total synthesis of ent-conduramine A and ent-deoxypancratistatin. Akgün, H.; Hudlicky, T. Tetrahedron Lett. 1999, 40, 3085.
  135. Toward a "reagent-free" synthesis: tandem enzymatic and electrochemical methods for increased effective mass yield (EMY). Hudlicky, T.; Frey, D. A.; Koroniak, L.; Claeboe, C. D.; Brammer, L. E. Jr. Green Chem. 1999, 1, 57.
  136. Minimum alveolar anesthethic concentration of fluorinated alkanols in rats: relevance to theories of narcosis. Eger, E. I.; Ionescu, P.; Laster, M. J.; Gong, D.; Hudlicky, T.; Kendig, J.; Harris, A.; Trudell, J. R.; Pohorille, A. Anesth. Analg.1999, 88, 867.
  137. Nonimmobilizers and transitional compounds may produce convulsions by two mechanisms. Eger, E. I.; Koblin, D. D.; Sonner, J.; Gong, D.; Laster, M. J.; Ionescu, P.; Halsey, M. J.; Hudlicky, T. Anesth. Analg. 1999, 88, 884.
  138. Electron transfer catalyzed [2+2] cycloreversion of benzene dimers. Reddy, G. D.; Weist, O.; Hudlicky, T.; Schapiro, V.; Gonzalez, D. J. Org. Chem. 1999, 64, 2860.
  139. Polyhalogenated methyl ethyl ethers: solubilities and anesthetic properties. Koblin, D. D; Laster, M. J.; Ionescu, P.; Gong, D.; Fang, Z. S.; Eger, E. I.; Halsey, M. J.; Terrell, R. C.; Hudlicky, T. Anesth. Analg. 1999, 88, 1161.
  140. Free radical cyclizations of trienes with tris(trimethylsilyl)silane. Restrepo–Sánchez, N. E.; Gomez, F. J.; Jaramillo–Gomez, L. M.<; Hudlicky, T. Synth. Commun. 1999, 29, 2795.
  141. New arene cis-dihydrodiol metabolites from ß-bromostyrenes. Novak, B. H.; Hudlicky, T. Tetrahedron: Asymmetry 1999, 10, 2067.
  142. The use of electrochemical methods as an alternative to tin reagents for the reduction of vinyl halides in inositol synthons. Hudlicky, T.; Claeboe, C. D.; Brammer, L. E.; Koroniak, L.; Butora, G.; Ghiviriga, I. J. Org. Chem. 1999, 64, 4909.
  143. Elucidation of the stereochemistry of octahydroisoquinoline derivatives by NMR spectroscopy. Ghiviriga, I.; Bottari, P. Q.; Hudlicky, T. Magn. Reson. Chem. 1999, 37, 653.
  144. Model study for a general approach to morphine and noroxymorphone via a rare Heck cyclization. Frey, D. A.; Duan, C.; Hudlicky, T. Org. Lett. 1999, 1, 2085.
  145. Design, synthesis, and biological evaluation of matrix metalloproteinase inhibitors derived from a modified proline scaffold. Cheng, M.; De, B.; Almstead, N. G.; Pikul, S.; Dowty, M. E.; Dietsch, C. R.; Dunaway, C. M.; Gu, F.; Hsieh, L. C.; Janusz, M. J.; Taiwo, Y. O.; Natchus, M. G.; Hudlicky, T.; Mandel, M. J. Med. Chem. 1999, 42, 5426.
  146. A short, stereoselective synthesis of neo-inositol. Hudlicky, T.; Restrepo–Sánchez, N.; Kary, P. D.; Jaramillo–Gómez, L. M. Carbohydrate Res. 2000, 324, 200.
  147. Practical preparation of potentially anesthetic fluorinated ethyl methyl ethers by means of bromine trifluoride and other methods. Hudlicky, T.; Duan, C.; Reed, J. W.; Yan, F.; Hudlicky, M.; Endoma, M. A.; Eger, E. I. J. Fluorine Chem. 2000, 102, 363.
  148. Comparison of approaches to ent-morphine via radical, cationic, and Heck-type cyclizations. Frey, D. A.; Duan, C.; Ghiviriga, I.; Hudlicky, T. Coll. Czech. Chem. Commun. 2000, 65, 561.
  149. Toluene dioxygenase-mediated oxidation of aromatic substrates with remote chiral centers. Bui, V.; Hansen, T. V.; Stenstrom, Y.; Ribbons, D. W.; Hudlicky, T. J. Chem. Soc. Perkin Trans. 1 2000, 1669.
  150. Direct biocatalytic synthesis of functionalized catechols: a green alternative to traditional methods with high effective mass yield. Bui, V. P.; Hansen, T. V.; Stenstrom,  Y.; Hudlicky, T. Green Chem 2000, 2, 263.
  151. A study of substrate specificity of toluene dioxygenase in processing aromatic compounds containing benzylic and/or remote chiral centers. Bui, V.P.; Hansen T.V.; Stenstrom, Y.; Hudlicky, T.; Ribbons, D. W. New J. Chem. 2001, 25, 116.
  152. Selective electrochemical reduction of cinnamyl ethers in the presence of other allylic C-O bonds. Solis-Oba, A.; Hudlicky, T.; Koroniak, L.; Frey, D. Tetrahedron Lett. 2001, 42, 1241.
  153. Chemoenzymatic synthesis of functionalized cyclohexylglycines and α-methylcyclohexylglycines via Kazmaier-Claisen rearrangement. Hudlicky, T.; Oppong, K.; Duan, C. M.; Stanton, C.; Laufersweiler, M. J.; Natchus, M. G. Bioorg. Med. Chem. Lett. 2001, 11, 627.
  154. Novel O- and N-linked inositol oligomers: A new class of unnatural saccharide mimics. Paul, B. J.; Martinot, T. A.; Willis, J.; Hudlicky, T. Synthesis 2001, 952.
  155. Synthesis of 2',3'-dideoxy-2',3'-didehydro nucleosides via a serendipitous route. Guo, Z.; Sanghvi, G. S.; Brammer, L. E.; Hudlicky, T. Nucleosides, Nucleotides & Nucleic Acids 2001, 20, 1263.
  156. The development of new carboxylic acid-based MMP inhibitors derives form a cycloheylglycine scaffold. Tullis, J. S.; Laufersweiler, M. J.; VanRens, J. C.; Natchus, M. G.; Bookland, R. G.; Almstead, N. G.; Pikul, S.; De, B.; Hsieh, L. C.; Janusz, M. J.; Branch, T. M.; Peng, S. X.; Jin, Y. Y.; Hudlicky, T.; Oppong, K. Bioorg. Med. Chem. Lett. 2001, 11, 1975.
  157. Opening of a vinyl aziridine with p-toluenesufonamide under TBAF catalysis: synthesis of 3,4-diamino-3,4-dideoxy-L-chiro-inositol. Paul, B. J.; Hobbs, E.; Buccino, P.; Hudlicky, T. Tetrahedron Lett. 2001, 42, 6433.
  158. Intramolecular Diels-Alder cycloadditions of cis-cyclohexadienediols derived enzymatically from (2-azidoethyl)benzene. Construction of highly functionalized bridged isoquinoline synthons. Hudlicky, T.; Zezula, J.; Ghiviriga I. Coll. Czech. Chem. Commun. 2001, 66, 1269.
  159. Convulsant and anesthetic properties of cis-trans isomers of 1,2-dichlorohexafluorocyclobutane and 1,2-dichloroethylene. Eger, E. I.; Halsey, M. J.; Koblin, D. D.; Laster, M. J.; Ionescu, P.; Königsberger, K.; Fan, R.; Nguyen, B. V.; Hudlicky, T. Anesth. Analg. 2001, 93, 922.
  160. Structure assignment of aminoconduritols by 15N-NMR correlation spectroscopy; synthesis of a positional isomer of 7-deoxypancratistatin. Schilling, S.; Rinner, U.; Chan, C.; Ghiviriga, I.; Hudlicky, T. Can. J. Chem. 2001, 79, 1659.
  161. Total synthesis of epi-7-deoxypancratistatin via aza-Payne rearrangement and intramolecular cyclization. Rinner, U.; Siengalewicz, P.; Hudlicky, T. Org. Lett. 2002, 4, 115.
  162. Direct biooxidation of arenes to corresponding catechols with E. coli JM109(pDTG602). Application to synthesis of combretastatins A-1 and A-2. Bui, V. P.; Hudlicky, T.; Hansen, T. V.; Stenstrøm, Y. Tetrahedron Lett. 2002, 43, 2839.
  163. Medium-scale preparation of useful metabolites of aromatic compounds via whole-cell fermentation with recombinant organisms. Endoma, M. A.; Bui, V. P.; Hansen, J.; Hudlicky, T. Org. Process Res. Dev. 2002, 6, 525.
  164. Enzymatic oxidation of cyclopropylbenzene: stuctures of new metabolites and possible mechanistic implications. Bui, V. P.; Nguyen, M.; Hansen, J. A.; Baker, J. M.; Hudlicky, T. Can. J. Chem. 2002, 80, 708.
  165. Total synthesis and biological evaluation of Amaryllidaceae alkaloids: narciclasine, ent-7-deoxypancratistatin, 7-deocypancratistatin, its 10ß-epimer, and truncated derivatives. Hudlicky, T.; Rinner, U.; Gonzalez, D.; Akgun, H.; Schilling, S.; Siengalewicz, P.; Martinot, T. A.; Pettit, G. R. J. Org. Chem. 2002, 67, 8726.
  166. Synthesis, structure, and biological evaluation of novel N- and O-linked diinositols. Paul, B. J.; Willis, J.; Martinot, T. A.; Ghiviriga, I; Hudlicky, T. J. Am. Chem. Soc. 2002, 124, 10416.
  167. Selective electrochemical deprotection of cinnamyl ethers, esters, and carbamates. Hansen, J.; Freeman, S.; Hudlicky, T. Tetrahedron Lett. 2003, 44, 1575.
  168. New applications of Burgess reagent in its reaction with epoxides. Rinner, U.; Adams, D. R.; dos Santos, M. L.; Hudlicky, T. Synlett 2003, 1247.
  169. Synthesis of chiral ADMET polymers containing repeating d-chiro-inositol units derived from a biocatalytically prepared diene diol. Bui, V. P.; Hudlicky, T. Tetrahedron 2004, 60, 641.
  170. Directed evolution of the dioxygenase complex for the synthesis of furanone flavor compounds. Newman, L. M.; Garcia, H.; Hudlicky, T.; Selifonov, S. A. Tetrahedron 2004, 60, 729.
  171. New oligomers of conduritol-F and muco-inositol. Synthesis and biological evaluationas glycosidase inhibitors. Freeman, S.; Hudlicky, T. Bioorg. Med. Chem. Lett. 2004, 14, 1209.
  172. Synthesis and biological activity of some structural modifications of pancratistatin. Rinner, U.; Hillebrenner, H. L.; Adams, D. R.; Hudlicky, T.; Pettit, G. R. Bioorg. Med. Chem. Lett. 2004, 14, 2911.
  173. Asymmetric dihydroxylation of cinnamonitrile to trans-3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]-acrylonitrile using chlorobenzene dioxygenase in Escherichia coli (pTEZ30). Yildirim, S.; Zezula, J.; Hudlicky, T.; Witholt, B.; Schmid, A. Adv. Synth. Catal. 2004, 346, 933.
  174. Enzymatic oxidation of thioanisoles: isolation and absolute configuration of metabolites. Finn, K. J.; Cankar, P.; Jones, T. R. B.; Hudlicky, T. Tetrahedron: Asymmetry 2004, 15, 2833.
  175. A ß-carboline-1-one mimic of the anticancer Amaryllidaceae constituent pancratistatin: synthesis and biological evaluation. Rinner, U.; Hudlicky, T.; Gordon, H.;Pettit, G. R. Angew. Chem. Int. Ed. 2004, 43, 5342.
  176. Reactions of Indole Derivatives with Oxiranes and Aziridines on Silica. Synthesis of 1-ß-Carbolin-1-one Mimic of Pancratistatin. Hudlicky, T.; Rinner, U.; Finn, K. J.; Ghiviriga, I. J. Org. Chem. 2005, 70, 3490.
  177. Selectivity in the electrochemical deprotection of cinnamyl groups from oxygen and nitrogen functionalities. Carbonates versus carbamates. Cankar, P.; Dubas, D.; Banfield, S. C.; Chahma, M.; Hudlicky, T. Tetrahedron Lett. 2005, 46, 6851.
  178. Cyclotrimerization Strategy toward Analogues of Amaryllidaceae Constituents. Synthesis of Deoxygenated Pancratistatin Core. Moser, M.; Sun, X.;Hudlicky, T. Org Lett. 2005, 7, 5669.
  179. Processing of cyclopropylarenes by toluene dioxygenase: isolation and absolute configuration of metabolites. Finn, K. J.; Rochon, L.; Hudlicky, T. Tetrahedron: Asymm. 2005, 16, 3606.
  180. Stability relationships in bicyclic ketones. Gordon, H. L.; Freeman, S.; Hudlicky, T. Synlett 2005, 2911.
  181. Toluene dioxygenase-mediated oxidation of bromo(methylsulfanyl) benzenes. Absolute configuration of metabolite and evaluation of chemo- and regioselectivity trends. Finn, K. J.; Pavlyuk, O.; Hudlicky, T. Coll. Czech. Chem. Commun. 2005, 70, 1709.
  182. Chemoenzymatic synthesis of complex natural and unnatural products: morphine, pancratistatin, and their analogs. Hudlicky, T. ARKIVOC 2006, 7, 276.
  183. Chiral version of the Burgess reagent and its reactions with epoxides. Leisch, H.; Saxon, R.; Sullivan, B.; Hudlicky, T. Synlett 2006, 445.
  184. Toluene dioxygenase-mediated oxidation of dibromobenzenes. Absolute stereochemistry of new metabolites and synthesis of (L)-conduritol E. Finn, K. J.; Collins, J.; Hudlicky, T. Tetrahedron 2006, 62, 7471.
  185. Convergent synthesis of 2,3-bisarylpyrazolones through cyclization of bisacylated pyrazolidines and hydrazines. Brugel, T. A.; Hudlicky, T.; Clark, M. P.; Golebiowski, A.; Sabat, M.; Endoma, M. A. A.; Bui, V.; Adams, D.; Laufersweiler, M. J.; Maier, J. A.; Bookland, R. G.; De, B. Tetrahedron Lett. 2006, 47, 3195.
  186. Cyclotrimerization approach to unnatural structural modifications of pancratistatin and other Amaryllidaceae constituents - Synthesis and biological evaluation. Moser, M.; Banfield, S. C.; Rinner, U.; Chapuis, J.-C.; Pettit, G. R.; Hudlicky, T. Can. J. Chem. 2006, 84, 1313.
  187. Convenient preparation of aryl-substituted nortropanes by Suzuki-Miyaura methodology. Ghosh, S.; Kinney, W. A.; Gauthier, D. A.; Lawson, E. C.; Hudlicky, T.; Maryanoff, B. E. Can. J. Chem. 2006, 84, 555.
  188. Studies on regioselective hydrogenation of thebaine and its conversion to hydrocodone. Leisch, H.; Carroll, R. J.; Hudlicky, T. ; Cox, D. Phillip Tetrahedron Lett. 2007, 48, 3979.
  189. Unexpected Reactivity of the Burgess Reagent with Thiols: Synthesis of Symmetrical Disulfides. Banfield, S. C.; Omori, A. T.; Leisch, H.; Hudlicky, T. J. Org. Chem. 2007, 72, 4989.
  190. Synthesis of deuterium-labelled chlorhexidine. Moser, M.; Hudlicky, T. ; S. Sadeghi, S.; Sternin, E. J. Label. Compd. Radiopharm. 2007, 50, 671.
  191. Chemoenzymatic Total Synthesis of (+)-Codeine by Sequential Intramolecular Heck Cyclizations via C-B-D Ring Construction. Omori, A. T.; Finn, K. J.; Leisch, H.; Carroll, R. J.; Hudlicky, T. Synlett 2007, 2859.
  192. Design for Morphine Alkaloids by Intramolecular Heck Strategy: Chemoenzymatic Synthesis of 10-Hydroxy-14-epi-dihydrocodeinone via C-D-B Ring Construction. Zezula, J.; Rice, K. C.; Hudlicky, T. Synlett 2007, 2863.
  193. Synthesis of 7-Deoxypancratistatin-1-carboxaldehyde and Carboxylic Acid via Solvent-Free Intramolecular Aziridine Opening: Phenanthrene to Phenanthridone Cyclization Strategy. Collins, J.; Drouin, M.; Sun, X.; Rinner, U.; Hudlicky, T. Org. Lett. 2008, 10 361.
  194. Chiral Version of the Burgess Reagent and Its Reactions with Oxiranes: Application to the Formal Enantiodivergent Synthesis of Balanol. Sullivan, B.; Gilmet, J.; Leisch, H.; Hudlicky, T. J. Nat. Prod. 2008, 71, 346.
  195. Preliminary investigation of the yeast-mediated reduction of ß-ketoamides derived from cyclic amines as potential resolution methodology. Saxon, R. E.; Leisch, H.; Hudlicky, T. Tetrahedron: Asymmetry 2008, 19, 672.
  196. Chemoenzymatic formal synthesis of (-)-balanol. Provision of optical data for an often-reported intermediate. Sullivan, B.; Hudlicky, T. Tetrahedron Lett. 2008, 49, 5211.
  197. Palladium-Catalyzed N-Demethylation/N-Acylation of Some Morphine and Tropane Alkaloids. Carroll, R. J.; Leisch, H.; Scocchera, E.; Cox, D. P. Hudlicky, T. Adv. Synth. Catal. 2008, 350, 2984.
  198. Formal total synthesis of (–)- and (+)-balanol: two complementary enantiodivergent routes from vinyloxiranes and vinylaziridines. Gilmet, J.; Sullivan, B.; Hudlicky, T. Tetrahedron 2009, 65, 212.
  199. One-Pot Conversion of Thebaine to Hydrocodone and Synthesis of Neopinone Ketal. Carroll, R. J.; Leisch, H.; Rochon, L.; Cox, D. P. Hudlicky, T. J. Org. Chem. 2009, 74, 747.
  200. New Options for the Reactivity of the Burgess Reagent with Epoxides in Both Racemic and Chiral Auxiliary Modes - Structural and Mechanistic Revisions, Computational Studies, and Application to Synthesis. Leisch, H.; Sullivan, B.; Fonovic, B.; Dudding, T.; Hudlicky, T. Eur. J. Org. Chem. 2009, 17, 2806.
  201. Symmetry-Based Design of the Chemoenzymatic Synthesis of Oseltamivir (Tamiflu) from Ethyl Benzoate. Sullivan, B.; Carrera, I.; Drouin, M.; Hudlicky, T. Angew. Chem. Int. Ed. 2009, 48, 23, 4229.
  202. Investigation of steric and functionality limits in the enzymatic dihydroxylation of benzoate esters. Versatile intermediates for the synthesis of pseudo-sugars, amino cylclitols, and bicyclic ring systems. Fabrizio, F.; Collins, J.; Sullivan, B.; Leisch, H.; Hudlicky, T. Org. Biomol. Chem. 2009, 7, 12, 2619.
  203. Biotransformations of Morphine Alkaloids by Fungi: N-Demethylations, Oxidations, and Reductions. Chaudhary, V.; Leisch, H.; Moudra, A.; Allen, B.; De Luca, V.; Cox, D.P.; Hudlicky, T. Collect. Czech. Chem. Comm. 2009, 74, 1179.
  204. Chemoenzymatic enantiodivergent syntheses of (+)- and (-)-codeine. Leisch, H.; Omori, A. T.; Finn, K. J.; Gilmet, J.; Bissett, T.; Ilceski, D.; Hudlicky, T. Tetrahedron 2009, 65, 9862.
  205. Short Chemoenzymatic Azide-Free Synthesis of Oseltamivir (Tamiflu): Approaching the Potential for Process Efficiency. Werner, L.; Machara, A.; Hudlicky, T. Advanced Synthesis and Catalysis 2010, 352, 195.
  206. Synthesis of 1,2- and 1,4-amino alcohols from 1,3-dienes via oxazines. Rearrangements of 1,4-amino alcohol derivatives to oxazolines. Werner, L.; Hudlicky, J. R.; Wernerova, M.; Hudlicky, T. Tetrahedron 2010, 66, 3761.
  207. Chemoenzymatic Synthesis of Amaryllidaceae Constituents and Biological Evaluation of their C-1 Analogues. The Next Generation Synthesis of 7-Deoxypancratistatin and trans-Dihydrolycoricidine. Collins, J.; Rinner, U.; Moser, M; Hudlicky, T. Journal of Organic Chemistry 2010, 76, 9, 3069.
  208. Design of Thermally Stable Versions of the Burgess Reagent: Stability and Reactivity Study. Metcalf, T. A.; Simionescu, R.; Hudlicky, T.  Journal of Organic Chemistry 2010, 75, 10, 3447.
  209. From Discovery to Application: 50 Years of the Vinylcyclopropane–Cyclopentene Rearrangement and Its Impact on the Synthesis of Natural Products. Reed, J. W.; Hudlicky, T. Angew. Chem. Int. Ed. 2010, 49, 4864.
  210. Recent chemoenzymatic total syntheses of natural and unnatural products: Codeine, balanol, pancratistatin, and oseltamivir. Hudlicky, T. Pure Appl. Chem. 2010, 82, 9, 1785.
  211. On the Practical Limits of Determining Isolated Product Yields and Ratios of Stereoisomers: Reflections, Analysis, and Redemption. Wernerova, M.; Hudlicky, T. Synlett 2010, 18, 2701.
  212. Chemoenzymatic Synthesis of Idesolide from Benzoic Acid. Adams, D. R.; Aichinger, C.; Collins, J.; Rinner, U.; Hudlicky, T.  Synlett 2011, 5, 725.
  213. Dauben-Michno oxidative transposition of allylic cyanohydrins - Enantiomeric switch of (-)-carvone to (+)-carvone. Hudlicky, J. R.; Werner, L.; Semak, V.; Simionescu, R.; Hudlicky, T. Can. J. Chem. 2011, 89, 535.
  214. A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen. Ma, D.; Tremblay, P.; Mahngar, K.; Akbari-Asi, P.; Collins, J.; Hudlicky, T.; McNulty, J.; Pandey, S. Invest. New Drugs 2011, 1.
  215. Synthesis of buprenorphine via N-demethylation of oripavine quaternary salts. Werner, L.; Machara, A.; Adams, D. R.; Cox, D. P.; Hudlicky, T. J. Org. Chem. 2011, 76, 4628-4634.
  216. Chemoenzymatic Total Synthesis of ent-Neopinone and Formal Total Synthesis of ent-Codeinone from β-bromoethylbenzene. Duchek, J.; Piercy, G.; Gilmet, J.; Hudlicky, T. Can. J. Chem. 2011, 89, 709-728.
  217. Synthesis of C-1 Homologues of Pancratistatin and their Preliminary Biological Evaluation. Vshyvenko, S.; Scattolon,  J.; Hudlicky, T.; Romero, A. E.; Kornienko, A. Bioorg. Med. Chem. Lett. 2011, 21, 4750-4752.
  218. A short synthesis of nonracemic iodocyclohexene carboxylate EF ring of kibledone congeners. Endoma-Arias, M. A. A.; Hudlicky, T. Tetrahedron Lett. 2011, 52, 6632-6634.
  219. Explorations of [4+2] and [5+2] cycloadditions of a dienylcyclopropane derived enzymatically form cyclopropylbenzene. Hudlicky, J. R.; Hopkins-Hill, J.; Hudlicky, T. Synlett 2011, 2891.
  220. Induction of apoptosis and autophagy in human pancreatic cancer cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin. Ma, D.; Tremblay, P.; Mahngar, K.; Akbari-Asl, P.; Collins, J.; Hudlicky, T.; Pandey, S. Am. J. Biomed. Sci. 2011, 3, 278-291.
  221. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process- Quality Synthesis, and Evaluation of Efficiency Metrics. Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.  J. Org. Chem. 2011, 76, 10050-10067.
  222. Synthesis of nalbuphine from oripavine via N-demethylation of N-cyclobutylmethyl oripavine quaternaty salt.   Machara,  A.;  D. Phillip Cox, D. P.; Hudlicky, T.  Heterocycles,  2012, 84, 615-623.
  223. Synthesis of morphine alkaloids and derivatives. Rinner, U.; Hudlicky, T.  Top. Curr. Chem.. 2012, 309, 33-66.
  224. Improved synthesis of buprenorphine from thebaine and/or oripavine via Pd-catalyzed N-demethylation/acylation and/or concomitant O-demethylation. Machara, A.;  Werner, L.; Endoma-Arias, M. A.; Cox, D. P.; Hudlicky, T. Adv. Synth. Catal. 2012, 354, 613-626.
  225. Toluene dioxygenase mediated oxidation of halogen-substituted benzoate esters. Semak, V.; Metcalf, T. A.; Endoma-Arias, M. A. A.; Mach, P.; Hudlicky, T.  Org. Biomol. Chem.. 2012, 10, 4407-4416.
  226. A novel C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen. Ma, D.; Tremblay, P.; Mahngar, K.; Akbari-Asl, P.; Collins, J.; Hudlicky, T.; McNulty, J.; Pandey, S.  Invest. New Drugs. 2012, 30, 1012-1027.
  227. Unnatural C-1 homologues of pancratistatin - synthesis and promising biological activities. Vshyvenko, S.; Scattolon, J.; Hudlicky, T.; Romero, A. E.; Kornienko, A.; Ma, D.; Tuffley, I.; Pandey, S.  Can. J. Chem.. 2012, 90, 932-943.
  228. Unexpected N-demethylation of oxymorphone and oxycodone N-oxides mediated by the Burgess reagent: Direct synthesis of naltrexone, naloxone, and other antagonists from oxymorphone. Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. A.; Duchek, J.; Adams, D. R.; Cox, D. P.; Hudlicky, T. Adv. Synth. Catal. 2012, 354, 2706-2712.
  229. Direct synthesis of naltrexone by palladium-catalyzed N-demethylation/actylation of oxymorphone: The benefit of C-H activation and intramolecular acyl transfer from C-14 hydroxy. Machara, A.; Cox, D. P.; Hudlicky, T. Adv. Synth. Catal. 2012, 354, 2713-2718.
  230. Application of D-chiro-inositol as a chiral template for the Diels-Alder reaction. Trant, J. F.; Belding, L.; Dudding, T.; Hudlicky, T. Helvetica Chimica Acta. 2012, 95, 2026-2035.
  231. On hype, malpractice, and scientific misconduct in organic synthesis. Carlson, R.; Hudlicky, T. Helvetica Chimica Acta. 2012, 95, 2052-2062.


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    Reviews, chapters, and books
    (*denotes publications by invitation)

    1. Formation of carbon–halogen bonds. Hudlicky, M.; Hudlicky, T. In Chemistry of Functional Groups, Supplement D; S. Patai, Z. Rappoport, eds.; John Wiley: New York, 1983; pp 1021–1172.
    2. * [Articles on terpenes, diterpenes, squalene, and isoprene.] Hudlicky, T. In The Encyclopedia of Science and Technology; McGraw–Hill, 1982.
    3. Hudlicky; M.; Hudlicky T. Formation of carbon-halogen bonds. In The Chemistry of Halides, Pseudo-halides, and Azides; The Chemistry of Functional Groups, Supplement D; Patai, S.; Rappoport, Z., Eds; John Wiley: New York, 1983; Part 2, Chapter 22, pp 1021-1172.
    4. * The vinylcyclopropane-cyclopentene rearrangement. Hudlicky, T.; Kutchan, T. M.; Naqvi, S. Organic Reactions 1985, 33, 247–335.
    5. General methodology for the synthesis of linear and nonlinear triquinane sesquiterpenes: Coriolin, pentalenene, and pentalenic acid. Hudlicky, T.; Natchus, M. G.; Sinai-Zingde G., Ranu, B. C.; Rigby, H. L., Andre, T. In Progress in Terpene Chemistry; Joulain, D., Ed.; Proceedings of the Conference on Terpene Chemistry, Grasse (France); Editions Frontières: Gif-sur-Yvette, France, 1986; pp 221–236.
    6. * Synthesis of cephalotaxine alkaloids. Hudlicky, T.; Kwart, L. D.; Reed, J. W. In Akaloids: Chemical and Biological Perspectives; S.W. Pelletier, Ed.; John Wiley: New York, 1987; Vol. 5, Chapter 5, pp 639–690.
    7. * [2+3] Carbo- and heterocyclic annulation in the design of complex molecules. Hudlicky, T.; Fleming, A.; Lovelace, T.; Seoane, G.; Gadamasetti, K.; Sinai-Zingde, G. In Strain and its Implications in Organic Chemistry; A. de Meijere, S. Blechert, Eds.; NATO ASI Series C, Kluwer Academic: Boston, 1989; Vol. 274; p. 109.
    8. * Use of cyclopropanes and their derivatives in organic synthesis. Wong, H. N. C.; Hon, M. Y.; Tse, C. W.; Yip, Y. Ch.; Tanko, J.; Hudlicky, T. Chem. Rev. 1989, 89, 165.
    9. * Synthesis of natural products containing five-membered rings. An evolution of general methodology. Hudlicky, T.; Rulin, F.; Lovelace, T. C.; Reed, J. W. In Studies in Natural Products Chemistry; Atta-ur-Rahman, ed.; Elsevier Science, 1989; Vol. 3, Part B, pp 3–72.
    10. *Hudlicky, T., Editor. Organic Synthesis: Theory and Applications; JAI Press: Greenwich, CT, 1989; Vol. 1.
    11. * Anionic approaches to the construction of cyclopentanoids. Hudlicky, T.; Price, J. D. Chem. Rev. 1989, 89, 1467.
    12. * Rearrangements of vinylcyclopropanes and related systems. Hudlicky, T.; Reed, J. W. In Comprehensive Organic Synthesis: Selectivity, Strategy & Efficiency in Modern Organic Chemistry; B.M. Trost, Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p. 899.
    13. Enzymatic hydroxylation of arenes and symmetry considerations in efficient synthetic design of oxygenated natural products. Hudlicky, T.; Fan, R.; Luna, H.; Olivo, H.; Price, J. (Proceedings of IUPAC Congress on Enzymes in Organic Synthesis, New Dehli, India, January 1992.) Pure Appl. Chem. 1992, 64, 1109; Ind. J. Chem. 1993, 32B, 154.
    14. Hudlicky, T.; Cebulak, M. Cyclitols and their Derivatives: A Handbook of Physical, Spectral, and Synthetic Data; VCH: New York, 1993.
    15. Divinylcyclopropane–cycloheptadiene rearrangement. Hudlicky, T.; Rulin, F.; Reed, J. W.; Gadamasetti, K. G. Organic Reactions1992, 41, 1–133.
    16. Efficient synthesis of optically active carbohydrates and other oxygenated compounds through bio-oxidation of chlorinated aromatics. Hudlicky, T. In Enzymes in Organic Synthesis; NATO ASI Series C; S. Servi, Ed.; Kluwer Academic: Boston, 1992; Vol. 381, p. 123.
    17. Hudlicky, T., Editor. Organic Synthesis: Theory and Applications; JAI Press: Greenwich, CT, 1993; Vol. 2.
    18. Modern synthetic design: symmetry, simplicity, efficiency, and art. Hudlicky, T.; Natchus M. G. In Organic Synthesis: Theory and Applications; Hudlicky, T., Ed.; JAI Press: London, 1993; Vol. 2, p. 1.
    19. The use of arene cis-diols in synthesis. Brown, S. M.; Hudlicky, T. In Organic Synthesis: Theory and Applications; T. Hudlicky, ed.; JAI Press: London, 1993; Vol. 2, p. 113.
    20. Enantioselective synthesis of alkaloids and carbohydrates via chemoenzymatic methods. Hudlicky, T. Pure & Appl. Chem. 1994, 66, 2067–2070.
    21. * An evolutionary perspective of microbial oxidations of aromatic compounds in enantioselective synthesis: history, current status, and perspectives. Hudlicky, T.; Reed, J. W. In Advances in Asymmetric Synthesis; A. Hassner, Ed.; JAI Press: London, 1995; Vol. 1, p 271.
    22. * Design constraints in practical syntheses of complex molecules: Current status, case studies with carbohydrates and alkaloids, and future perspectives. Hudlicky, T. Chem. Rev. 1996, 96, 3. 
    23. * Environmentally efficient management of aromatic compounds. Economic perspectives of biocatalytic conversion of aromatics to optically pure synthons for the pharmaceutical industry. Hudlicky, T. In Green Chemistry. Designing Chemistry for the Environment; Anastas, P. T., Williamson, T. C., Eds.; ACS Symposium Series 626; American Chemical Society: Washington, D. C., 1996; Chapter 14.
    24. * A historical perspective of morphine syntheses. Hudlicky, T.; Butora, G.; Fearnley, S.; Gum, A.; Stabile, M. In Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier: Amsterdam, 1996; Vol 18, p 43.
    25. * Formation of five-membered rings: Vinylcyclopropane–cyclopentene rearrangement. Hudlicky, T.; Becker, D. A.; Fan, R. L.; Kozhushkov, S. In Carbocyclic Three-membered Ring Compounds; Houben–Wyel, 1996; Vol. E 17c, p. 2538.
    26. * Formation of seven-membered rings: Divinylcyclopropane–cycloheptadiene rearrangement. Hudlicky, T.; Fan, R. L.; Becker, D. A.; Kozhushkov, S. In Carbocyclic Three-membered Ring Compounds; Houben–Wyel, 1996; Vol. E 17c, p. 2589.
    27. Hudlicky, T., Editor. Organic Synthesis: Theory and Applications; JAI Press: Greenwich, CT, 1996; Vol. 3.
    28. * Modern methods of monosaccharide synthesis from non-carbohydrate sources. Hudlicky, T.; Entwistle, D. A.; Pitzer, K. K.; Thorpe, A. J. Chem. Rev. 1996, 96, 1195.
    29. Hudlicky, T., Guest Editor. Current Organic Chemistry—Asymmetric Synthesis 1997, 1 (1).
    30. * The Cephalotaxus alkaloids—a review. Miah, M. A. J.; Hudlicky, T.; Reed, J. W. In The Alkaloids: Chemistry and Biology; Cordell, G. A., Ed.; Academic Press: San Diego, 1998; Vol 51, pp 199–269.
    31. Hudlicky, T., Editor. Organic Synthesis: Theory and Applications; JAI Press: Stamford, CT, 1998; Vol. 4.
    32. The story of morphine structure elucidation: one hundred years of deductive reasoning. Butora, G.; Hudlicky, T. Organic Synthesis: Theory and Applications; Hudlicky, T., Ed.; JAI Press: Stamford, CT, 1998; Vol. 4, pp 1–51.
    33. Hudlicky, T., Guest Editor. Current Organic Chemistry—Asymmetric Synthesis 1998, 2 (3).
    34. Green chemistry alternatives for the processing of aromatic compounds. Tandem strategies in biocatalysis and synthesis. Hudlicky, T. In Green Chemistry: Frontiers in Benign Chemical Synthesis and Processes; Anastas, P. T., Williamson, T. C., Eds.; Oxford University Press: Oxford, 1998; Chapter 10, pp 166–177.
    35. * Natural product synthesis via biocatalysis: an essay of the merits of multidisciplinary ventures. Hudlicky, T. J. Braz. Chem. Soc. 1998, 9, 1.
    36. Hudlicky, T., Guest Editor. Current Organic Chemistry—Asymmetric Synthesis 1999, 3 (3).
    37. *Enzymatic dihydroxylation of aromatics in enantioselective synthesis: expanding asymmetric methodology. Hudlicky, T.; Gonzalez, D.; Gibson, D. T. Aldrichimica Acta 1999, 32, 35.
    38. Hudlicky, T., Guest Editor. Current Organic Chemistry—Asymmetric Synthesis 2000, 4 (3).
    39. Morphine synthesis and biosynthesis—an update. Novak, B. H.; Hudlicky, T.; Reed, J. W.; Mulzer, J.; Trauner, D. Curr. Org. Chem.2000, 4, 343–362.
    40. *Recent progress in efficient syntheses of Amaryllidacae and morphine alkaloids. J. Heterocyclic Chem. 2000, 37, 535–539.
    41. *Biocatalytic synthesis of alkaloids and carbohydrates: an update. Hudlicky, T. In Enzymes in Action; Zwanenburg, B. Ed.; NATO ASI Series; Kluwer Academic, Dordrecht, 2000; pp 311-321.
    42. Hudlicky, T., Guest Editor. Current Organic Chemistry-Asymmetric Synthesis 2001, 5 (4).
    43. Hudlicky, T., Editor. Organic Synthesis: Theory and Applications; JAI Press: Stamford, CT, 2001; Vol. 5.
    44. Hudlicky, T. Guest Editor. Current Organic Chemistry-Asymmetric Synthesis 2002, 6 (4).
    45. Hudlicky, T. Guest Editor. Current Organic Chemistry-Asymmetric Synthesis 2003, 7 (17).
    46. Hudlicky, T. Guest Editor. Current Organic Chemistry-Asymmetric Synthesis 2004, 8 (14).
    47. Hudlicky, T. Book review: Bommarius, A. S.; Riebel, B. R. Biocatalysis. Fundamentals and Applications; Wiley-VCH: Weinheim, Germany, 2004. J. Nat. Prod. 2005, 68, 150.
    48. Synthesis of Amaryllidaceae Constituents - An Update. Rinner, U.; Hudlicky, T. Synlett. 2005, 365.
    49. Recent Progress in the Synthesis of Morphine Alkaloids. Zezula, J.; Hudlicky, T. Synlett, 2005, 388.
    50. Celebrating 20 Years of SYNLETT- Special Account On the Merits of Biocatalysis and the Impact of Arene cis-Dihydrodiols on Enantioselective Synthesis. Reed, J. W.; Hudlicky, T. Synlett, 2009, 685.
    51. Applications of biotransformations and biocatalysis to complexity generation in organic synthesis. Reed, J.; Hudlicky, T. Chem. Soc. Rev. 2009, 38, 3117.
    52. From Discovery to Application: 50 Years of the Vinylcyclopropane–Cyclopentene Rearrangement and Its Impact on the Synthesis of Natural Products. Reed, J.; Hudlicky, T. Angew. Chemie. Int. Ed. 2010, 49, 4864.
    53. Introduction to Enzymes in Synthesis. Hudlicky, T. Chem. Rev. 2011, 111, 3995-3997.
    54. Chemoenzymatic Synthesis of Inositols, Conduritols, and Cyclitol Analogues.  Duchek, J.; Adams, D. R.; Hudlicky, T.  Chem. Rev. 2011, 111, 4223-4258.
    55. Synthesis of morphine alkaloids and derivatives. Rinner, U.; Hudlicky, T. Top. Curr. Chem. 2012, 309, 33-66.


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    Patents
     

    1. Synthesis of sugars from substituted and unsubstituted arene diols. Hudlicky, T. U.S. Patent 5 200 516, 1993.
    2. Synthesis of cyclitols from substituted arene diols. Hudlicky, T. U.S. Patent 5 306 846, 1994.
    3. Method for preparing erythuronolactone. Hudlicky, T. U.S. Patent 5 442 079, 1995.
    4. Synthesis of sphingosines. Hudlicky, T. U.S. Patent 5 488 166, 1996.
    5. Synthesis of sphingosines. Hudlicky, T. U.S. Patent 5 488 167, 1996.
    6. Syntheses of D-chiro-3-inosose and (+)-D-chiro-inositol. Hudlicky, T.; Mandel, M. U.S. Patent 5 563 281, 1996.
    7. Syntheses of D-chiro-3-inosose and (+)-D-chiro-inositol. Hudlicky, T.; Mandel, M. U.S. Patent 5 578 738, 1996.
    8. Synthesis of (+)-pancratistatin. Hudlicky, T.; Tian, X.; Konigsburger, K. U.S. Patent 5 627 280, 1997.
    9. Syntheses of D-chiro-3-inosose and (+)-D-chiro-inositol. Hudlicky, T.; Mandel, M. U.S. Patent 5 600 014, 1997.
    10. Syntheses of D-chiro-3-inosose and (+)-D-chiro-inositol. Hudlicky, T.; Mandel, M. U.S. Patent 5 602 263, 1997.
    11. Syntheses of D-chiro-3-inosose and (+)-D-chiro-inositol. Hudlicky, T.; Mandel, M. U.S. Patent 5 602 287, 1997.
    12. Syntheses of D-chiro-3-inosose and (+)-D-chiro-inositol. Hudlicky, T.; Mandel, M. U.S. Patent 5 633 412, 1997.
    13. Method for preparing erythruronolactone. Hudlicky, T.; Mandel, M. European patent EP 0 698 026 B1, 1998.
    14. Synthesis of conduritol epoxides and aziridines and methods of using such to synthesize higher oligosaccharides. Hudlicky, T. U.S. Patent 5 834 606, 1998.
    15. Syntheses of D-chiro-3-inosose and (+)-D-chiro-inositol. Hudlicky, T.; Mandel, M. Australian Patent 693075, 1998.
    16. Process for preparing a morphinan derivative. Hudlicky, T.;Butora, G. U.S. Patent 5 912 347, 1999.
    17. Conversion of thebaine to morphine derivatives. Carroll, R. J.; Leisch, H.; Hudlicky, T. U.S. Pat. Appl. Publ., 2009, US  2009005563.
    18. Conversion of thebaine to morphine derivatives. Carroll, R. J.; Leisch, H.; Hudlicky, T.; Cox, D. P. PCT Int. Appl., 2009, WO  2009003271.
    19. Methods for N-demethylation of morphine and tropane alkaloids.  Carroll, R. J.; Leisch, H.; Hudlicky, T. U.S. Pat. Appl. Publ.  (2009), US  2009005564.
    20. Methods for N-demethylation of morphine and tropane alkaloids. Carroll, R. J.; Leisch, H.; Hudlicky, T. PCT Int. Appl.  (2009), WO  2009003272  A1  20090108  AN 2009:20617.
    21. Methods for one-pot N-demethylation/N-acylation of morphine and tropane alkaloids. Carroll, R. J.; Leisch, H.; Hudlicky, T.; Cox, D. P. U.S. Pat. Appl. Publ. US  2009005565, 2009. 
    22. Methods for one-pot N-demethylation/N-acylation of morphine and tropane alkaloids. Carroll, R. J.; Leisch, H.; Hudlicky, T.; Cox, D. P.  PCT Int. Appl.  (2009), WO  2009003270.
    23. Hudlicky, T. Processes for the preparation of Tamiflu and analogs thereof and intermediates thereof. U.S. Patent applied for, provisional application # 61/052435 (filed May 12, 2008).
    24. Novel C-1 analogs of pancratistatin and 7-deoxypancratistatin and processes for their preparation. Hudlicky, T.; Collins, J. Canadian Patent applied for (filed December 23, 2008).
    25. Process for the preparation of methylnaltrexone bromide and derivatives thereof. Hudlicky, T.; Leisch, H.; Carroll, R. US Provisional patent application 61/172,521, filed April 24, 2009.
    26. Hudlicky, T. Processes for the preparation of Oseltamivir and analogs thereof. U.S. Patent applied for, International  PCT Application No. PCT/CA2009/000622  (filed May 12, 2009).
    27. Process for the preparation of intermediates useful for the manufacture of oseltamivir and analogs. Hudlicky, T.; Werner, L.; Machara, A.; US Provisional patent application 61/254311, filed October 23, 2009.
    28. Novel C-1 analogs of pancratistatin and 7-deoxypancratistatin and processes for their preparation. Hudlicky, T.; Collins, J. PCT filed December 12, 2009.
    29. Process for the preparation of methylnaltrexone bromide and derivatives thereof. Hudlicky, T.; Leisch, H.; Carroll, R. US Provisional patent application 61/172,521, filed April 24, 2009.
    30. Hudlicky, T. Processes for the preparation of Oseltamivir and analogs thereof. U.S. Patent applied for, International  PCT Application No. PCT/CA2009/000622  (filed May 12, 2009).
    31. Process for the preparation of intermediates useful for the manufacture of oseltamivir and analogs. Hudlicky, T.; Werner, L.; Machara, A.; US Provisional patent application 61/254311, filed October 23, 2009.
    32. Novel C-1 analogs of pancratistatin and 7-deoxypancratistatin and processes for their preparation. Hudlicky, T.; Collins, J., PCT filed December 12, 2009.
    33. Novel C-1 analogs of pancratistatin and 7-deoxypancratistatin and processes for their preparation. Hudlicky, T.; Collins, J.   Can. Pat. Appl.  (2010),     60pp.  CODEN: CPXXEB  CA  2647655  A1  20100623  CAN 153:116470.
    34. Novel C-1 analogs of pancratistatin and 7-deoxypancratistatin and processes for their preparation. Hudlicky, T.; Collins, J.   PCT Int. Appl.  (2010),     67pp.  CODEN: PIXXD2  WO  2010069054  A1  20100624  CAN 153:116469.
    35. Processes and intermediates for the preparation of oseltamivir and analogs thereof for treatment of influenza. Hudlicky, T.   PCT Int. Appl.  (2009),     106pp.  CODEN: PIXXD2  WO  2009137916  A1  20091119  CAN 151:570946.
    36. Processes for the preparation of morphinane and morphinone compounds. Hudlicky, T.; Carroll, R.; Leisch, H.; Machara, A.; Werner, L.; Adams, D. R.  PCT Int. Appl. PCT/CA2010/000587 (2010),  102pp.  CODEN: PIXXD2  WO  2010121369  A1  20101028  CAN 153:555396  AN 2010:1342585.
    37. Processes and Intermediates in the Preparation of Morphine Analogs via N-Demethylation of N-Oxides Using Burgess Reagent. Hudlicky, T.; Machara, A.; Werner, L.; Wernerova, M.; Endoma-Arias, M. A. US Provisional Patent Application No: 61/489,359. Filing Date: May 2, 2011.
    38. Process for the Preparation of Morphine Analogs via Metal Catalyzed N-Demethylation/Functionalization and Intramolecular Group Transfer. Hudlicky, T.; Machara, A. US Provisional Patent Application No: 61/483,264. Filing Date: May 6, 2011
    39. Methods for One-Pot N-Demethylation/N-Functionalization of Morphine and Tropane Alkaloids. Hudlicky, T.; Carroll, R.; Leisch, H.; Machara, A.; Werner, L.; Endoma-Arias, M. A. US CIP Application No: 13/178,623; Filing Date: July 8, 2011


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